RecruitingNAINTERVENTIONAL

Descriptive Study of the Reconstruction of Osteochondral Lesions of the Knee: Clinical and Imaging Results

This study is investigating surgical treatments for a specific type of knee problem where the cartilage and bone underneath are damaged, known as an osteochondral defect. Doctors are looking at two main ways to fix this: using a patient's own cartilage (autologous reconstruction) or using a special natural material (collagen matrix) to help new cartilage grow. The purpose is to see how well these treatments help patients feel better and if the improvements can be seen on MRI scans. Currently, there isn't much information available about how well these particular treatments work in the long term, so this study aims to fill that gap. It's a way to learn more about improving recovery and understanding the healing process for these knee injuries.

At a glance

Status

Recruiting

Phase

Sponsor

Versailles Hospital

Enrolment target

130

Start

01 Apr 2019

Estimated completion

01 Jun 2035

Osteochondral Defect

What is this study about?

Imagine the smooth, slippery surface at the ends of your bones in a joint – that's cartilage. In your knee, this cartilage helps your bones glide smoothly past each other. Sometimes, this cartilage, and a little bit of the bone underneath it, can get damaged. This is called an osteochondral defect or lesion, and it can cause pain, swelling, and difficulty moving your knee.

Doctors have different ways to try and fix these problems. This study is focusing on two specific surgical approaches. One method involves taking some of a person's healthy cartilage from another part of their body and moving it to the damaged area in the knee. This is like a transplant using your own tissue. The other method uses a special material, often made from collagen, which acts like a scaffold to encourage new cartilage to grow in the damaged spot.

The main goal of this study is to understand how well these two treatments work. The researchers want to see if people feel better, if their knee function improves, and what the healing looks like on special scans called MRIs. This is important because there isn't a lot of detailed information about the long-term results of these particular treatments, especially when looking at both how someone feels and what the imaging shows. By gathering this information, doctors can learn more about which treatments might be best for people with these knee issues.

Key takeaways

This study evaluates specific knee cartilage repair surgeries.
It focuses on using your own tissue or a special collagen material.
Researchers will check patient outcomes and MRI scans.
The goal is to understand long-term results for these treatments.
Participation involves sharing medical information and follow-up assessments.

Who may be eligible?

To be part of this study, you need to be an adult, 18 years or older, who has had surgery on your knee to repair damaged cartilage and the bone underneath. This surgery must have used either your own cartilage transplanted to the area, or a special collagen material to help new cartilage grow.

You would not be able to join this study if your knee surgery involved other types of cartilage repair techniques. Also, if you had this type of cartilage repair surgery on a joint other than your knee, this study would not be the right fit for you. The study is specifically focused on knee reconstructions using these two techniques.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Have you had knee surgery for damaged cartilage and bone?
Did your surgery use your own cartilage or a collagen material to fix it?
Was this surgery performed only on your knee, and not another joint?
Was your surgery not another type of cartilage repair technique?

Answer every question to see your result.

What does participation involve?

This study is gathering information from people who have already had specific knee surgeries. It's a 'descriptive' study, which means researchers are observing and collecting data rather than testing a new treatment or asking you to do something new. You would likely be asked to attend clinic visits where healthcare professionals will assess your knee. They will also review your medical records, including details about your surgery and any follow-up appointments. A key part of the study involves taking MRI scans of your knee, which are special pictures that show the cartilage and bone in detail. The total duration of your participation would depend on how long the research team needs to follow your progress and collect information about your recovery.

Potential risks and benefits

Participating in this study primarily involves allowing researchers to collect and review information about a surgery you've already had and attend follow-up assessments, including MRI scans. The benefits of participating include contributing valuable information that could help other people with similar knee conditions in the future, as there is currently limited data on these specific treatments. As such, there are no direct medical risks from participating, beyond those inherent in routine follow-up appointments and MRI scans, which are generally very safe. You are free to withdraw from the study at any time without giving a reason, and this decision will not affect your medical care.

Locations (1)

CH de Versailles
Verified postcode
Le Chesnay, France· Recruiting

Common questions

What kind of knee problem is this study looking at?

It's looking at knee problems where both the cartilage (the smooth surface) and the bone underneath are damaged, often called an osteochondral defect.

What treatments are being studied?

The study is looking at two types of surgery: using your own healthy cartilage to fix the damaged area, or using a special collagen material to help new cartilage grow.

Why is this study important?

There isn't much information about how well these specific knee surgeries work in the long term, so this study hopes to provide clearer answers and improve future treatments.

Will I have to take new medication?

No, this study doesn't involve new medications. It's about looking at the results of surgeries that have already taken place or will take place as part of your standard care.

What is an MRI scan?

An MRI is a special type of scan that uses magnets and radio waves to create detailed pictures of the inside of your body, including your knee joints and cartilage.

How to find out more

Nicolas PUJOL

npujol@ch-versailles.fr +33139639565 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.