Not yet recruitingNAINTERVENTIONAL

Ovarian Cancer Screening and AI

Many specialist doctors who treat women (gynaecologists) might think ovarian cancer screening is more helpful and safer than it truly is. This study wants to see if using a special computer program, or AI, can help correct these ideas. We're testing if an AI conversation that shares clear, fact-based information about ovarian cancer screening can help gynaecologists understand the real benefits and risks better. This could lead to them making more accurate recommendations for women, compared to just having a general AI chat about how common ovarian cancer is. The goal is to make sure women get the most accurate and helpful advice possible.

At a glance

Status

Not yet recruiting

Phase

Sponsor

Charite University, Berlin, Germany

Enrolment target

350

Start

27 Mar 2026

Estimated completion

30 Apr 2026

Ovarian Cancer Screening Recommendations by Gynecologists

What is this study about?

This study is all about making sure women get the best and most accurate advice about screening for ovarian cancer. It's been found that gynaecologists, who are specialist doctors for women's health, sometimes believe that ovarian cancer screening is more effective and safer than scientific evidence suggests. This can lead to women getting tests they might not actually need, which can cause unnecessary worry or even other problems.

Researchers are now exploring whether a type of computer programme called Artificial Intelligence (AI) can help. They are testing if an AI tool that talks to gynaecologists about ovarian cancer screening – explaining the facts and clearing up any misunderstandings – can improve the doctors' knowledge. The hope is that by giving gynaecologists better information, they will revise their advice and recommendations to patients, focusing on what the science truly shows.

Essentially, the study randomly divides gynaecologists into two groups. One group talks with an AI that specifically discusses the evidence around screening benefits and harms. The other group has a general chat with AI about how often ovarian cancer occurs. By comparing the recommendations made by doctors in both groups before and after their AI chat, the researchers will see if the AI discussion made a difference in how gynaecologists advise their patients.

Key takeaways

The study aims to improve doctors’ understanding of ovarian cancer screening.
It uses AI conversations to help doctors learn about the true benefits and risks.
The goal is for doctors to give more accurate, evidence-based advice to women.
No patients are directly involved in medical tests as part of this study.
This research focuses on improving healthcare communication and reducing unnecessary procedures.

Who may be eligible?

This study is looking for women's health doctors, called gynaecologists, who work in clinics and regularly suggest ovarian cancer screening (like a special ultrasound or blood test called CA 125) to their patients. These are patients who don't have any symptoms and aren't at higher risk than average.

To be clear, the study is specifically looking for gynaecologists whose current practice of recommending screening to these women goes against general medical advice for people without symptoms or specific risk factors.

Doctors who work in hospitals (inpatient care) or gynaecologists who do not usually recommend ovarian cancer screening to average-risk patients without symptoms are not eligible to take part in this study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you a gynaecologist (women's health doctor)?
Do you work in an outpatient clinic (not a hospital ward)?
Do you currently recommend ovarian cancer screening (like ultrasound or CA 125 test) to women who don't have symptoms and aren't at high risk?
Are your patients generally at 'average risk' for ovarian cancer, meaning no strong family history or known genetic risks?

Answer every question to see your result.

What does participation involve?

This study doesn't involve any medical procedures, medication, or follow-up appointments for patients. It's focused on understanding how doctors give advice. If you were a gynaecologist taking part, you would first answer some questions about your current understanding of ovarian cancer screening and what advice you usually give. Then, you'd have a conversation with an AI program. After the AI chat, you'd answer similar questions again to see if your understanding or advice has changed. The total time commitment for a gynaecologist participating in this study would be quite short, likely just one session.

Potential risks and benefits

This study is designed to improve how doctors understand and talk about ovarian cancer screening, which could ultimately benefit many women by ensuring they receive accurate, evidence-based advice. There are no direct medical risks to patients as this study focuses on doctors' knowledge, not patient treatment. Participants (gynaecologists) have the right to withdraw from the study at any time without giving a reason.

Locations (1)

Charité - Universitätsmedizin Berlin
Verified postcode
Mitte, Germany

Common questions

What is ovarian cancer screening?

Ovarian cancer screening usually involves tests like a special ultrasound scan of the ovaries or a blood test called CA 125. The aim is to try and find cancer early in people who don't have any symptoms.

Is ovarian cancer screening recommended for all women?

No, for women who don't have symptoms and are at average risk (meaning no strong family history or genetic risks), routine ovarian cancer screening is generally not recommended by medical guidelines because it hasn't been shown to save lives overall and can sometimes lead to unnecessary worry or procedures.

What is AI?

AI stands for Artificial Intelligence. It's a computer program designed to think and learn, and in this study, it's used to have conversations and share information.

Why is this study important?

This study is important because it wants to make sure that doctors have the most up-to-date and accurate information about ovarian cancer screening. This helps them give the best possible advice to their patients, avoiding unnecessary tests or worries.

Who can take part in this study?

This study is for gynaecologists (women's health doctors) who regularly recommend ovarian cancer screening to their patients who do not have symptoms and are at average risk.

How to find out more

Odette Wegwarth, Prof. Dr.

odette.wegwarth@charite.de +49 30 450 531 074 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.