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Active not recruitingOBSERVATIONAL

Biological and Clinical Database for Pancreatic Adenocarcinoma

This project, called BACAP, is collecting samples of blood, saliva, and tumor tissue, along with health information, from patients with pancreatic cancer. It's a big effort funded by a French cancer institute and coordinated by experts. The main aim is to create a high-quality resource that scientists can use to research pancreatic cancer. By studying these samples, researchers hope to uncover new ways to diagnose the cancer earlier, find markers that predict how patients might respond to treatment, and ultimately develop more effective therapies. This collection will be valuable for improving care for future patients.

At a glance

Status
Active not recruiting
Sponsor
University Hospital, Toulouse
Enrolment target
1,700
Start
01 May 2014
Estimated completion
01 Jan 2029

What is this study about?

Pancreatic cancer, specifically pancreatic adenocarcinoma, is a serious illness, being one of the leading causes of cancer death in Western countries. Unfortunately, it's often diagnosed at a late stage, and surgery, which is the best chance for a cure, is only possible for a small number of patients. Also, it's difficult to prevent or screen for because we don't have clear warning signs or reliable tests.

This project, called BACAP, aims to tackle these challenges. It's creating a special collection, often called a biobank, of biological samples (like blood, saliva, and tissue from tumors) and detailed medical information from patients with pancreatic cancer. This isn't just any collection; it's being built to the highest quality standards across many hospitals in France. The researchers hope that by studying these samples, along with the patients' health information, they can identify new patterns and 'markers' that will help diagnose the cancer earlier and develop more effective treatments.

A key part of this project is collecting various types of samples, including tumor tissue from surgeries and also from specific biopsies taken using a technique called endoscopic ultrasonography. This allows them to get samples even from tumors that can't be surgically removed. All the valuable DNA and RNA from these samples will be used for detailed molecular analyses. This whole effort is about accelerating research and finding better ways to help people with pancreatic cancer.

Key takeaways

  • BACAP is a French research project collecting samples and data from pancreatic cancer patients.
  • The goal is to build a high-quality resource for scientists to improve diagnosis and treatment.
  • Participation involves donating samples (like blood/tissue) usually taken during routine care.
  • No new treatments or procedures are given as part of this study.
  • Your contribution helps advance critical research into pancreatic cancer.
  • You can withdraw from the study at any time.

Who may be eligible?

To join this study, you need to be at least 18 years old. You must have received a definite diagnosis of pancreatic adenocarcinoma, which is a specific type of pancreatic cancer. This diagnosis would have been confirmed by laboratory tests on a tissue sample.

Also, your pancreatic mass (the tumor) must have been looked at in detail using scans like a CT scan or a special ultrasound technique called endoscopic ultrasonography with a fine-needle aspiration.

It's very important that you understand the study and agree to take part by signing a consent form. If for any reason you are unable or unwilling to sign this form, if you are pregnant, or if your pancreatic cancer diagnosis hasn't been officially confirmed, you wouldn't be able to join the study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 18 years old or older?
  2. Do you have a confirmed diagnosis of pancreatic adenocarcinoma?
  3. Has your pancreatic mass been investigated by CT scan or EUS with fine-needle aspiration?
  4. Are you able to understand and sign an informed consent form?
  5. Are you not pregnant?
Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you won't be undergoing any new treatments or procedures specifically for the study. Instead, the study will involve collecting biological samples like blood, saliva, and tissue from your pancreatic tumor. These samples would typically be taken during procedures you are already having for your diagnosis or treatment, such as blood tests or biopsies. Your medical information, including how your disease progresses and how you respond to your treatments, will also be collected over time. The exact duration of your participation isn't specified, but it generally involves collecting samples and data as part of your ongoing care.

Potential risks and benefits

Taking part in this study primarily involves donating samples that are often collected during routine medical procedures, so there are typically no additional direct risks beyond those associated with your standard care. The main benefit for participants is knowing they are contributing to significant research that could lead to better understanding, diagnosis, and treatment for pancreatic cancer in the future. You always have the right to withdraw from the study at any time without it affecting your medical care.

Locations (16)

  • University Hospital Bordeaux
    Verified postcode
    Bordeaux, France
  • Beaujon Hospital
    Verified postcode
    Clichy, France
  • University Hospital Lille
    Verified postcode
    Lille, France
  • University Hospital of Lille
    Verified postcode
    Lille, France
  • Centre Léon Bérard
    Verified postcode
    Lyon, France
  • Private Hospital Jean Mermoz
    Verified postcode
    Lyon, France
  • Hopital La Timone
    Verified postcode
    Marseille, France
  • Hospital Nord
    Verified postcode
    Marseille, France
  • Institut Regional du Cancer de Montpellier
    Verified postcode
    Montpellier, France
  • University Hospital Montpellier
    Verified postcode
    Montpellier, France
  • University Hospital of NICE
    Verified postcode
    Nice, France
  • Saint-Louis Hospital
    Verified postcode
    Paris, France

Common questions

What is a biobank?

A biobank is like a library that stores biological samples (like blood or tissue) and health information for research, helping scientists learn more about diseases.

Will taking part in BACAP change my current treatment?

No, taking part in BACAP will not change your current treatment plan. This study focuses on collecting samples and data, not on providing new treatments.

Who will have access to my samples and information?

Only authorised scientists involved in pancreatic cancer research will have access to your anonymised samples and information. Your personal details will be kept confidential.

What is 'endoscopic ultrasonography fine-needle aspiration'?

It's a procedure where a thin, flexible tube with an ultrasound on the end is passed into your body to get tiny tissue samples from your pancreas for diagnosis or research.

Can I still withdraw from the study after joining?

Yes, you can withdraw from the study at any time without giving a reason, and it will not affect the medical care you receive.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Discussion

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