To investigate the safety and efficacy of a novel investigational compound against neurological diseases such as Parkinson's disease in healthy men and women and patients with Parkinson's disease.
Researchers are testing a new experimental drug designed to treat neurological conditions, with a focus on Parkinson's disease. Parkinson's is a condition that affects the brain and causes movement problems like tremors, stiffness, and slow movement. This study is a Phase I trial, which means it is the very first time this medicine is being given to humans. The main goal is to find out if the drug is safe, what side effects it might cause, and how the body handles it. Because this is an early safety trial, it involves both healthy adult volunteers and people who have been diagnosed with Parkinson's disease. Participants must be at least 18 years old. Taking part helps scientists understand whether this new compound could become an effective treatment for nerve diseases in the future.
At a glance
What is this study about?
Parkinson's disease is a condition where nerve cells in the brain slowly lose function over time. This leads to common symptoms such as trembling, stiff muscles, and trouble with balance or walking. While current treatments can help manage these symptoms, they cannot stop the condition from progressing. This clinical trial is looking at a completely new medicine that scientists hope could help treat neurological conditions like Parkinson's in the future.
Because this is a 'Phase I' trial, it represents the very first step in testing the drug in people. Before this stage, the compound was only tested in laboratory settings. The main aim right now is not necessarily to cure the condition, but to see how safe the drug is, check for any unwanted side effects, and find out how it travels through and leaves the body.
Trials like this are vital for medical progress. Without them, no new medicines could ever reach the clinic or the NHS. By checking the drug in both healthy volunteers and people living with Parkinson's disease, the research team can build a full, clear picture of how the medicine works in different bodies.
Key takeaways
- Tests a brand-new medicine for Parkinson's disease in humans for the first time.
- Aimed primarily at checking safety and finding any side effects.
- Open to both healthy adults and people living with Parkinson's disease.
- Participants must be aged 18 or older.
- Requires clinic visits and health tests to monitor your safety closely.
Who may be eligible?
This study is open to adults aged 18 and over, including both men and women. The researchers are looking for two groups of people: healthy volunteers who do not have serious long-term illnesses, and people who have received a confirmed diagnosis of Parkinson's disease.
To keep everyone safe, there will be strict medical checks before anyone can join. These checks usually mean that people with certain other serious health issues, like severe heart, liver, or kidney problems, may not be able to take part. Pregnant or breastfeeding women are also usually excluded from early-stage drug trials.
If you are interested, the study doctors will review your medical history and current medications in detail to decide whether it is safe and suitable for you to join.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- I am at least 18 years old.
- I am either in good general health OR I have been diagnosed with Parkinson's disease.
- I am able and willing to travel to a trial clinic for check-ups.
- I am comfortable having routine tests, such as blood draws and heart traces.
- I am not currently pregnant or breastfeeding.
What does participation involve?
Taking part in this study involves several stages. First, you will attend a screening appointment where doctors will check your general health through blood tests, heart traces (ECGs), and physical exams. If you are eligible, you will be given the study medicine, which might be taken as a tablet or an injection. Because this is a first-in-human trial, you may need to stay at a specialist clinic or hospital ward for close monitoring for a short time after taking the dose. Throughout the trial, you will have regular check-ups, provide blood and urine samples, and complete simple health questionnaires. The full study duration varies, but it typically lasts from a few weeks to several months, including follow-up visits to check on your recovery and well-being.
Potential risks and benefits
Locations (1)
- —UnverifiedNetherlands
Common questions
What is a Phase I clinical trial?
A Phase I trial is the earliest stage of testing a new treatment in people. Its main goal is to check safety, find the right dose, and see how the human body processes the medicine.
Why are healthy people needed for a Parkinson's trial?
Testing healthy volunteers helps doctors see how the medicine works in a body without the condition, making it easier to spot side effects and understand the drug's basic behaviour.
Will this medicine cure my Parkinson's disease?
No, this trial is not expected to cure Parkinson's disease. It is an early test to see if the drug is safe enough to be tested in larger, future studies.
Will taking part cost me anything?
No, clinical trial medicines and tests are free. Many trials also help cover travel expenses, and healthy volunteers may sometimes receive compensation for their time.
Can I leave the study if I change my mind?
Yes. Joining is completely voluntary, and you can choose to stop taking part at any time without it affecting your normal medical care.
How to find out more
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
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