CompletedPhase IInterventional

Multifocal contact lenses dispensing validation study

As we get older, many people find it harder to read small print. This normal change is called presbyopia. At the same time, many people have astigmatism, where an uneven eye shape causes blurred vision. It can be hard to correct both conditions with a single contact lens. This clinical trial tests a new soft, daily disposable contact lens called the ERIS toric multifocal. It is designed to provide clear vision at all distances while also correcting astigmatism. Participants will attend two clinic appointments. At the first visit, the eye care team will fit the trial lenses. You will wear them for 8 to 12 days before returning for a final check-up to assess your comfort, eye health, and how well you can see. The study aims to confirm whether these lenses work well for everyday use.

At a glance

Status

Completed

Phase

Phase I

Sponsor

CooperVision International Limited (United Kingdom)

Enrolment target

Start

10 Nov 2025

Estimated completion

12 Mar 2026

Presbyopia, astigmatism

What is this study about?

From around the age of 40, our eyes naturally start to lose their ability to focus on close objects, such as books, phones, or computer screens. This condition is called presbyopia. Many people also have astigmatism, which happens when the clear front of the eye is shaped more like a rugby ball than a round football, causing blurred or stretched vision. Around four in ten people who need reading help also have astigmatism.

Finding a single contact lens that can correct both issues comfortably can be challenging. To help address this, researchers are developing a new daily disposable soft contact lens called the ERIS toric multifocal. Daily disposable lenses are worn once and thrown away each night, which many people find clean and convenient. These new lenses are designed to correct astigmatism while simultaneously providing clear sight for near, intermediate, and distance vision.

This study is testing how well the new lenses perform in everyday life. Over a short trial period, researchers will check how easy the lenses are to fit, how comfortable they feel throughout the day, and how well they help wearers see. The results will help determine whether this new lens design is effective and ready for wider use.

Key takeaways

Testing a new daily disposable contact lens for people with both presbyopia and astigmatism.
Open to current soft contact lens wearers aged 40 and older.
Involves two clinic visits and wearing the trial lenses for 8 to 12 days.
Aims to check lens comfort, quality of vision, and fit.
Participation is entirely voluntary and you can leave at any time.

Who may be eligible?

This study is looking for adults aged 40 and older who already wear soft contact lenses and need vision correction for both astigmatism and reading. To join, your eyes must be generally healthy aside from needing vision correction, and your spectacle prescription must fall within the specific ranges required for this study.

You cannot take part if you have an active eye infection, eye inflammation, a history of eye surgery, or conditions affecting the cornea (the clear front surface of the eye). The trial is also not suitable for people who have functional vision in only one eye, those who are pregnant or breastfeeding, or people taking certain medications that may make wearing contact lenses unsafe.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 40 years old or older?
Do you currently wear soft contact lenses?
Do you have astigmatism and need reading correction?
Are your eyes free from active infections or past eye surgeries?
Are you able to attend two clinic visits over a two-week period?

Answer every question to see your result.

What does participation involve?

Taking part involves two visits to an eye clinic in London. At your first visit, an eye specialist will examine your eyes and fit you with the trial contact lenses. Up to three fitting attempts may be made to ensure you get the best possible fit and vision. Once fitted, you will take the daily disposable lenses home and wear a fresh pair each day for 8 to 12 days. You will carry on with your normal daily routine during this time. At your second visit, the study team will test your eyesight, evaluate the health of your eyes, and ask you about your comfort and visual satisfaction. The entire study lasts under two weeks for each participant.

Potential risks and benefits

You may benefit from trying a new type of lens designed specifically for your vision needs, but there is no guarantee it will improve your sight compared to your current lenses. As with any contact lenses, there is a small risk of mild eye irritation, dryness, or a corneal infection, although serious infections are very rare when lenses are used properly. Your eyes will be closely checked by trained specialists during the visits. Taking part is completely voluntary, and you are free to stop wearing the study lenses and leave the trial at any time without giving a reason.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

Ocular Technology Group International
City only
London, England

Common questions

What are daily disposable contact lenses?

Daily disposable lenses are soft contact lenses that you put in each morning and throw away before going to sleep. You do not need to clean or store them overnight.

Does it cost anything to take part?

No, the trial lenses and all study appointments are provided free of charge.

Can I keep wearing my usual glasses or lenses during the study?

During the 8 to 12 day wearing period, you will be asked to wear the study contact lenses. You can switch back to your normal glasses if you need to remove the study lenses for any reason.

What happens if the trial lenses are uncomfortable?

You can remove the lenses immediately if your eyes feel uncomfortable, painful, or red. You should contact the study team to let them know.

Where does the study take place?

The study visits take place at the Ocular Technology Group - international (OTG-i) clinic in the UK.

How to find out more

Deborah Moore

dmoore@otg.co.uk +44 (0)2072224224 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.