AuthorisedTherapeutic use (Phase IV)Interventional

Measles-mumps-rubella vaccine (MMR) at 6 months of age: Long-term follow-up

This study is checking how well the Measles, Mumps, and Rubella (MMR) vaccine protects children over a long time. It looks at children who have already had their routine MMR vaccinations. Specifically, researchers are testing blood samples from children 1 to 3 years after their four-year-old MMR jab, and again at least a year after their second MMR jab, to measure their immunity. The main goal is to see how strong their protection against measles is, and they'll also check for protection against mumps and rubella. This helps us understand the long-lasting effects of the vaccine.

At a glance

Status

Authorised

Phase

Therapeutic use (Phase IV)

Sponsor

Rigshospitalet

Enrolment target

1,000

Start

08 Jun 2026

Prevention of measles, mumps, and rubella by vaccination

What is this study about?

This study is exploring how well your child is protected against common childhood diseases like measles, mumps, and rubella after they've had their routine MMR vaccinations. The MMR vaccine is a very important jab that helps protect children from these illnesses. Doctors and scientists want to understand how long this protection lasts. They are specifically focusing on children who have already received their routine MMR vaccinations.

To do this, researchers will be looking at blood samples. They will check the levels of protective substances, called antibodies, in the blood. These antibodies tell us how strong a child's immunity is. The first check will happen 1 to 3 years after a child's first MMR jab, which is usually given around 4 years of age. They will also look at antibody levels at least a year after a child's second MMR jab.

The main aim is to see how strong the child's protection against measles is over time. They will also check for protection against mumps and rubella. This sort of long-term check helps make sure the vaccine continues to provide good protection and helps doctors understand the best vaccination schedules for children. It's all about making sure children stay healthy and protected.

Key takeaways

The study assesses how well the MMR vaccine protects over time.
It focuses on children who have already received their routine MMR vaccinations.
Researchers will check blood samples for protection against measles, mumps, and rubella.
This helps verify the long-lasting effectiveness of the vaccine.
Participation involves routine follow-up blood tests, not new treatments.

Who may be eligible?

This study is looking for children of any age and of all sexes. Essentially, if your child has received their routine MMR vaccinations, they might be able to take part.

Because this study is looking at the long-term effects of the MMR vaccine, it focuses on children who have already had their jabs. There are no specific age limits; children from babies to teenagers could potentially be involved, as long as they fit the vaccination criteria. There are also no restrictions based on whether your child is a boy or a girl.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Has your child received their routine MMR vaccinations?
Is your child any age?
Do you consent to your child having blood tests?
Are you happy for your child to be followed up over time?

Answer every question to see your result.

What does participation involve?

This study is about following up on children who have already received their routine MMR vaccinations. It's likely to involve taking a blood sample at specific times – for example, 1 to 3 years after their 4-year-old MMR jab, and again at least a year after their second MMR jab. This would probably mean a visit to a clinic or hospital for each blood test. There shouldn't be any new medication or interventions involved, as this study is observing the effects of vaccinations already given. The total duration for each child's involvement would depend on how many follow-up blood tests are needed over time.

Potential risks and benefits

Taking part in this study could offer reassurance about the long-term effectiveness of the MMR vaccine for your child and contribute to better understanding of vaccine protection for all children. The main potential risk would be discomfort from a blood test, which is usually minor and temporary. As with any study, you have the right to withdraw your child at any time, for any reason, without it affecting their medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Denmark

Common questions

What is the MMR vaccine?

The MMR vaccine is a jab given to children to protect them from three serious illnesses: measles, mumps, and rubella.

Why is this study important?

This study helps us understand how long the MMR vaccine protects children, ensuring it continues to keep them safe from these diseases.

Will my child receive a new vaccine in this study?

No, this study is observing children who have already had their routine MMR vaccinations. No new vaccines are given.

What does 'immunity' mean?

Immunity means your body has protection against a particular illness, often because it has made special cells called antibodies.

How long will my child be involved?

Your child's involvement will depend on the schedule of blood tests, which usually happen at specific points after their vaccinations.