A new device to examine raised level of proteins during inflammation
This study is looking at a new, fast way to detect high levels of certain proteins in the blood, which are often raised when someone has a serious infection or inflammation, like a lung infection. Currently, testing for these proteins can take a long time. The new device, called a microfluidic device, aims to give results much quicker, directly where the patient is. This could help doctors diagnose conditions like sepsis (a severe reaction to infection) more rapidly, decide on the best treatment sooner, and ultimately improve patient care and save lives. This initial study will use a small blood sample already taken for routine tests to see if the new device works effectively.
At a glance
What is this study about?
When your body fights off an infection, especially a serious one like a lung infection, it can release special proteins into your blood. High levels of these proteins, like Interleukin-6 (IL-6), tell doctors that your body is working hard to fight the infection, but sometimes this fight can become overwhelming. Quickly knowing if these protein levels are high can help doctors understand how severe your infection is and make important decisions about your care sooner.
Currently, it can take a while to get these test results back because blood samples often need to be sent to a lab. This wait can mean a delay in diagnosis and treatment. This study is testing a new, tiny device that we hope will be able to check these protein levels much faster, right at the patient's bedside or in the clinic. Imagine getting results in minutes rather than hours, which could be hugely helpful for doctors and patients alike. This early study will help us understand if this new device works well and is a step towards it being used more widely.
Ultimately, if this new device is successful, it could help doctors quickly identify patients who need urgent care for serious infections, leading to earlier treatment. This could potentially save lives and improve recovery for many people. It's about giving doctors better tools to make fast, informed decisions when every minute counts.
Key takeaways
- This study is testing a new, rapid device for detecting infection markers.
- It aims to help doctors diagnose and treat serious infections like lung infections faster.
- No extra blood samples are needed; existing samples will be used.
- There are no direct benefits to you for participating, but it aids medical progress.
- No identified risks or discomfort for participants.
- All personal information will be kept anonymous.
Who may be eligible?
This study is looking for adults aged 18 and over who have recently been admitted to the hospital. You might be eligible if you've been in the hospital for less than three days (72 hours) and the doctors suspect you have a lung infection.
Lung infections being considered for this study include flare-ups of chronic obstructive pulmonary disease (COPD), pneumonia, or infections that developed while you were in the hospital or on a ventilator.
You wouldn't be able to join if your doctors think your infection or inflammation is coming from somewhere other than your lungs, if you're unable to give your consent, or if you have an underlying cancer.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Have you been admitted to the hospital with a suspected lung infection (like pneumonia or COPD flare-up)?
- Have you been in the hospital for less than 72 hours (3 days)?
- Are your doctors sure your infection isn't from somewhere else in your body?
- Are you able to provide your consent to take part?
- Do you not have an underlying cancer?
What does participation involve?
If you decide to take part in this study, it's quite simple. You won't need to have any extra blood taken. Instead, a very small amount of blood that has already been drawn for your regular hospital tests will be used for the study. After you give your consent, a small portion of this existing blood sample will be separated in the lab and used to test how well the new device works. There are no additional visits or follow-up appointments specifically for this study.
Potential risks and benefits
Locations (1)
- Medway NHS Foundation TrustCity onlyGillingham, England
Common questions
What is IL-6?
IL-6 is a protein your body makes when it's fighting an infection or dealing with inflammation. High levels can mean a more serious condition.
Why is a faster test needed?
Faster test results mean doctors can quickly understand how severe your infection is and start the right treatment sooner, which can improve your recovery.
Will I have to give extra blood?
No, you will not have to give any extra blood. The study will use a small part of a blood sample already taken for your routine hospital tests.
Will this help me directly?
This study won't directly change your treatment now, but it will help develop better ways to diagnose and treat serious infections for future patients.
Is my information kept private?
Yes, all your information will be made anonymous, meaning it can't be linked back to you, to protect your privacy.
How to find out more
Rahuldeb Sarkar
Always speak to your GP or specialist before deciding to take part in a study.
Discussion
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