A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

To join this study, people generally need to be at least 18 years old and have small cell lung cancer that has been confirmed by a doctor. This cancer must also have come back after you've had at least one round of chemotherapy with platinum-based drugs. Your doctors will need to be able to measure your cancer, meaning they can see and track its size. You should also be generally well enough to take part in a study, as judged by your doctor, and able to do most of your daily activities.

There are also some reasons why you might not be able to join. For example, if you've already had many rounds of treatment for your cancer, or if you've recently had other cancer medications. Certain other health conditions, like severe lung problems or serious heart issues, could also prevent you from participating. Your doctor will review all your health information carefully to see if this study is suitable for you.

If you decide to take part, you'll be given either the new medicine, ZL-1310, or a treatment your doctor would normally choose. This will involve regular visits to the clinic for check-ups, blood tests, and scans to see how you're responding to the treatment. You might be asked to provide a small sample of your tumour (a biopsy) or existing tissue from a previous biopsy for extra tests. The doctors and nurses will monitor you closely for any side effects or changes in your health. The total time you'll be in the study will depend on how your treatment progresses, but you'll have regular follow-up appointments.