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RecruitingNAINTERVENTIONAL

Influence of Sodium Intake in spondyLoarthriTes

The SALT study is investigating the connection between how much salt you eat and how active your spondyloarthritis is. Researchers want to understand if dietary salt intake plays a role in the disease activity for people with axial spondyloarthritis or psoriatic arthritis. This research could help us learn more about managing these conditions. By carefully measuring participants' salt intake, the study aims to uncover any potential links that might lead to new advice or treatments in the future. It's an observational study, meaning it will look at existing patterns rather than testing a new medicine.

At a glance

Status
Recruiting
Phase
NA
Sponsor
Centre Hospitalier Universitaire de Besancon
Enrolment target
250
Start
30 Jan 2024
Estimated completion
01 May 2027

What is this study about?

This research, called the SALT study, is looking into something quite interesting: whether the amount of salt in our diets affects joint conditions like axial spondyloarthritis and psoriatic arthritis. Spondyloarthritis is a type of arthritis that mainly affects the spine and sometimes other joints, while psoriatic arthritis affects people who also have psoriasis, causing joint pain, stiffness, and swelling.

Researchers are keen to understand if there's a clear link between how much salt someone eats and how active their disease is. 'Disease activity' refers to how much inflammation, pain, or stiffness a person is experiencing. By gathering information on both salt intake and disease activity, the study hopes to find patterns that could help us better understand and potentially manage these conditions in the future.

It's important to remember that this study isn't testing a new medicine. Instead, it's observing and collecting data to see if a relationship exists. The findings from studies like this are crucial because they can help doctors and patients make more informed choices about diet and lifestyle, which might eventually lead to feeling better.

Key takeaways

  • The study investigates the link between salt intake and spondyloarthritis activity.
  • It's for people with axial spondyloarthritis or psoriatic arthritis.
  • No new medicines are involved; it's an observational study.
  • Helps researchers understand disease management better.
  • Participation involves measuring current salt intake and health assessments.

Who may be eligible?

The study is looking for people aged 18 to 80 years old, both men and women, who have been diagnosed with axial spondyloarthritis (this includes both those whose condition shows up on X-rays and those where it doesn't) or psoriatic arthritis.

For women, you can join if you have already gone through menopause (meaning no periods for at least two years), have had a procedure to prevent pregnancy (like having your tubes tied), or are using reliable birth control methods (like birth control pills, injections, coils, patches, or using two forms of barrier contraception, like condoms with a diaphragm).

However, some people cannot take part. This includes if you are pregnant, or if you are currently taking certain medications, such as cyclosporine, water tablets (diuretics), or specific blood pressure medicines (angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists). Also, if you are currently taking or have recently taken (in the last six months) certain specific biologic medications (like secukinumab, ixekizumab, ustekinumab, and others mentioned in the original text) or high doses of steroids (more than 10mg of prednisolone equivalent), you won't be able to join this particular study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you between 18 and 80 years old?
  2. Do you have axial spondyloarthritis or psoriatic arthritis?
  3. Are you NOT pregnant?
  4. Are you NOT currently taking specific treatments like cyclosporine or high-dose steroids?
  5. Have you NOT recently (last 6 months) taken certain biologic medications (e.g., secukinumab, ustekinumab)?
Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you won't be given any new medicines to try. Instead, the study will mainly involve measuring your current salt intake. This could involve keeping a food diary or providing samples for analysis over a period of time, as well as regular assessments to check your disease activity. The study does not mention specific visits or a total duration, but you would likely have a few appointments to provide this information and have your condition assessed by the research team. You'll be asked questions about your diet and your overall health. There will be no follow-up treatment provided as part of this study.

Potential risks and benefits

The main benefit of taking part is contributing to a better understanding of spondyloarthritis and psoriatic arthritis, which could help others in the future. You won't receive a new treatment, but you might gain a clearer picture of your own health and diet habits. There are very few direct risks with this type of observational study, as it mainly involves collecting information and measurements, not experimental treatments. You are always free to change your mind and stop participating in the study at any time, for any reason, without it affecting your usual medical care.

Locations (4)

  • CHU Besançon
    Verified postcode
    Besançon, France· Recruiting
  • CHD Vendée
    Verified postcode
    La Roche-sur-Yon, France· Recruiting
  • CHU St Etienne
    Verified postcode
    Saint-Etienne, France· Recruiting
  • Hôpital Nord Franche-Comté
    Verified postcode
    Trévenans, France· Recruiting

Common questions

What kind of salt are they looking at?

They are looking at the overall amount of sodium (salt) you consume in your diet from all food sources.

Will I have to eat less salt if I join?

No, this study is observing your current salt intake. You won't be asked to change your diet as part of the research.

What is 'axial spondyloarthritis'?

It's a type of arthritis that mainly causes pain and stiffness in your spine and sometimes other joints.

Will my own doctor know I'm in the study?

Your research team will discuss with you how your personal doctor will be informed, usually with your permission.

How long will I be involved in the study?

The information provided doesn't specify an exact duration, but the research team will explain the full timeline to you before you agree to participate.

How to find out more

Guillaume BOITEUX, PhD

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Influence of Sodium Intake in spondyLoarthriTes…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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