Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome
This study is gathering information from people across the UK who have specific types of head and neck cancer, including cancers of the mouth, throat, and voice box. It’s not testing new drugs, but rather observing how patients are treated in real life with existing medicines, especially newer types of immunotherapy. Doctors want to learn more about how different treatments affect patients and how certain things in their body (called biomarkers) might help predict which treatments work best. This will help them improve care for others in the future. The study is particularly interested in understanding better treatments for advanced cancers that have come back or spread.
At a glance
What is this study about?
This study is like a large collection of information about patients with certain types of head and neck cancer. These cancers include those of the mouth (oral cavity), parts of the throat (oropharynx and hypopharynx), and the voice box (larynx). The doctors running this study want to understand the different ways these cancers are treated in everyday hospitals and clinics across the country. They are particularly interested in seeing how people respond to newer treatments, like those that boost the body's immune system.
Imagine doctors are building a very detailed picture of what's happening in hospitals right now. It's not a trial where you would get a new experimental drug; instead, it's about carefully watching and recording how different established treatments are used, for example, new therapies called 'checkpoint inhibitors'. They also want to explore if certain clues in your body, called 'biomarkers', can help predict which treatments will work best for whom. This information is key to figuring out the best order and combination of treatments. By collecting all this information, they hope to improve care for future patients.
This is especially important for cancers that have come back or spread, as well as for less common types of head and neck cancers where there isn't one clear best treatment yet. By understanding what's currently being done and how patients are doing, researchers can quickly identify gaps in knowledge and find ways to make treatments more effective and personalised. It's all about making sure patients get the right treatment at the right time.
Key takeaways
- This study collects information about treated head and neck cancer patients.
- It aims to understand how existing treatments, especially newer immunotherapies, are working.
- No new medicines or experimental treatments are given as part of this study.
- Your regular medical care will not change if you participate.
- The information gathered could help improve treatments for future patients.
- You can stop taking part at any time without affecting your care.
Who may be eligible?
To be part of this study, you need to be at least 18 years old. You should have a confirmed diagnosis of certain types of head and neck cancer, specifically squamous cell carcinoma of the mouth, certain parts of the throat, or the voice box.
The study is for people whose cancer can't be cured with current treatments and who are receiving either palliative care (treatment to manage symptoms and improve quality of life) or the best supportive care available. You also need to be able to understand the study and agree to take part by signing a consent form.
There are no reasons listed that would prevent you from joining if you meet the above requirements. For most patients, it's about agreeing to join within four weeks of starting your first treatment for advanced cancer. If you're receiving only supportive care, you'd need to agree to join within six weeks of finding out your cancer had come back or spread.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you 18 years old or older?
- Do you have confirmed squamous cell carcinoma of the mouth, throat, or voice box?
- Is your cancer at an advanced stage where a cure is not possible, and you're receiving palliative or best supportive care?
- Can you understand and sign a consent form to agree to join the study?
What does participation involve?
If you choose to take part in this study, you won't be given any new or experimental treatments. Instead, the study will simply collect information about the treatment you are already receiving as part of your standard care. This means you will continue with your usual doctor's appointments, tests, and medications. The study team will gather details from your medical records, such as your diagnosis, the treatments you receive, how you respond to them, and your general health over time. There are no extra hospital visits or special procedures required just for this study. It's a way for doctors to learn from your real-world experience without changing your medical care.
Potential risks and benefits
Locations (2)
- Universitätsklinikum EssenVerified postcodeEssen, Germany· Not yet recruiting
- Onkologie/Studienzentrum am Raschplatz GbRVerified postcodeHanover, Germany· Recruiting
Common questions
What kind of cancer is this study about?
This study focuses on specific types of head and neck cancer, including cancers of the mouth, throat, and voice box.
Will I receive new medicine if I join this study?
No, this study only collects information about the standard treatments you are already receiving; it does not involve giving new medicines.
Do I need extra doctor visits for this study?
No, you will have your normal appointments and usual care. The study team will just collect information from your existing medical records.
What is the study hoping to achieve?
It aims to learn more about how current treatments work in real life and to find better ways to use them for other patients in the future.
Can I leave the study once I've joined?
Yes, you can choose to stop participating in the study at any time, and this will not affect your medical care.
How to find out more
Project Manager
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
Community discussion
Powered by our forum at community.patient.info. Please be respectful — this is not medical advice.