Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases

To take part in this study, you could be a child or an adult who has been diagnosed with a rare autoimmune or autoinflammatory disease that started before they were 18. This includes conditions like lupus or certain types of arthritis. We are also looking for family members of people with these conditions.

There are a few health requirements: participants must weigh more than 5 kilograms (about 11 pounds) and be signed up for a social security scheme. Importantly, you and your parents or guardians (if you're under 18) must understand what the study involves and agree to take part by signing a consent form.

We are also looking for healthy volunteers, both children and adults, of any age who weigh more than 5 kilograms and are part of a social security scheme. However, healthy volunteers cannot join if they have an active infection, have had cancer in the last five years, have a personal or family history of autoimmune disease, or have a weakened immune system.

Taking part in this study primarily involves donating a blood sample. This blood sample will be used for several different tests. Researchers will look at your genes (your DNA) to see if there are any specific genetic changes linked to your condition. They will also examine your immune system's responses and look for special markers in your blood that might indicate the disease. This is a "bio-collection" study, which means we are gathering samples to store for future research; it doesn't involve new medication or regular doctor's visits related to the study. It's a one-off donation that helps build this important collection for research.