RecruitingNAINTERVENTIONAL

Neural Signatures of Processing the Temporal Features of Auditory Events: From Preterm Infancy to Adulthood

This study is investigating how the brains of premature babies react to sounds. Premature babies, especially those born between 25 and 36 weeks of pregnancy, are still developing many important connections in their brains. Researchers are using two safe and gentle methods, EEG and NIRS, to measure brain activity when these babies hear different sounds. EEG involves placing small sensors on the baby's scalp, and NIRS uses light near the baby's head. By understanding how these tiny brains process sound, the study aims to learn more about normal brain development and why some premature babies might face developmental challenges later on.

At a glance

Status

Recruiting

Phase

Sponsor

Centre Hospitalier Universitaire, Amiens

Enrolment target

240

Start

01 Feb 2020

Estimated completion

01 Feb 2027

Time Perception EEG Premature Neonates Discrimination

What is this study about?

This study is about understanding how the brains of premature babies develop, particularly how they react to sounds. When babies are born very early, their brains are still making important connections. This period, especially between 25 and 36 weeks of pregnancy, is a crucial time for brain growth and development.

Researchers want to see if they can detect early signs of how well a premature baby's brain is developing. They believe that if the brain isn't forming connections in the usual way, it might explain why some premature babies face developmental difficulties as they grow up.

By carefully observing how these babies' brains respond to different sounds, the study hopes to gain new insights into how brain networks are formed and identify potential issues early on. This knowledge could eventually help doctors provide better support for premature babies and their families.

Key takeaways

This study helps understand premature baby brain development.
It focuses on how premature baby brains respond to sounds.
Safe, gentle tests (EEG and NIRS) are used to measure brain activity.
Participation is brief and involves no medication.
Understanding early brain development could help premature babies in the future.

Who may be eligible?

To be able to take part in this study, babies must have been born prematurely. They need to be between 25 and 36 weeks gestational age. This means we are looking at babies who are very premature and still developing a lot in the womb-like environment of the hospital.

Babies who were born at full term, or those who are outside the 25 to 36-week gestational age range, will not be able to join this particular study. This study specifically focuses on the very early stages of development in prematurely born infants.

There are no gender restrictions, meaning both baby boys and baby girls can participate if they meet the gestational age requirement.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Is my baby a premature baby?
Was my baby born between 25 and 36 weeks gestational age?
Is my baby currently aged between 0 days to 1 day after birth (very early on)?
Is my baby able to participate in a gentle, non-invasive assessment session?

Answer every question to see your result.

What does participation involve?

If your baby is eligible to participate, they would have some gentle tests. These tests involve placing small sensors on their head to measure brain activity (EEG) and using a special light device (NIRS) to look at blood flow in the brain. These procedures are non-invasive and carried out while your baby is resting comfortably. There will be no medication involved. Each session will be relatively brief, and the total duration of your baby's participation in the study will be very short, usually consisting of one or two assessment sessions lasting no more than a day in total.

Potential risks and benefits

Participating in this study might help us learn more about brain development in premature babies, which could benefit future children. The procedures (EEG and NIRS) are considered very safe and non-invasive, with no known risks or side effects for the baby. You have the right to withdraw your baby from the study at any time, for any reason, without it affecting their medical care.

Locations (1)

CHU Amiens
Verified postcode
Amiens, France· Recruiting

Common questions

What is Gestational Age?

Gestational age is how far along the pregnancy was when your baby was born, measured from the first day of the mother's last menstrual period.

What is an EEG?

An EEG (electroencephalogram) is a test that measures electrical activity in the brain using small sensors placed gently on the scalp. It is painless.

What is NIRS?

NIRS (Near-Infrared Spectroscopy) is a method that uses light to measure blood flow and oxygen levels in the brain, also completely pain-free for your baby.

Will my baby feel any pain?

No, both EEG and NIRS are completely painless and non-invasive. Your baby will be comfortable throughout the assessment.

How long will my baby's participation last?

Your baby's involvement will typically consist of one or two short assessment sessions, completed within a single day.

How to find out more

Fabrice Wallois, Pr

fabrice.wallois@u-picardie.fr (33)322087775 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.