All studies
CompletedInterventional

Early rehabilitation promoting motor recovery from spinal cord injury

A spinal cord injury in the neck or upper back often weakens the torso muscles, making everyday tasks like sitting upright or moving in and out of a wheelchair difficult. In the early weeks after an injury, the body has a strong natural ability to repair damaged nerve connections. Researchers at the University of Birmingham are investigating whether using a simple arm bike (arm-crank exercise) can help rebuild these pathways. In this UK trial, adults with a recent spinal cord injury will either receive standard NHS rehabilitation or standard care plus arm-bike training. Those in the exercise group will train for 20 to 30 minutes, five days a week, for eight weeks. Researchers will measure arm strength, sitting balance, and overall quality of life to see if this low-cost therapy speeds up recovery.

At a glance

Status
Completed
Sponsor
University of Birmingham
Enrolment target
30
Start
01 Aug 2022
Estimated completion
31 Aug 2023

What is this study about?

When a person damages their spinal cord in their neck or upper back, messages between the brain and the body can be interrupted. This often leads to weakness in the torso muscles that support posture. Without good control of the stomach and back muscles, sitting upright, washing, dressing, and transferring between a bed and a wheelchair can feel unstable and tiring. Currently, torso rehabilitation needs heavy support from physiotherapists, which can limit how often patients get to practise.

Scientists have discovered that exercising the arms can naturally stimulate and strengthen the nerve pathways connected to the torso. This effect means people may be able to use parts of their body that still work well to help rebuild parts affected by the injury. Using a simple, table-top arm bike allows people to exercise safely with less hands-on assistance.

In the first couple of months following a spinal injury, the nervous system is primed to heal. This study tests whether introducing arm-bike training during this crucial early window leads to greater, longer-lasting recovery. Taking place at specialist spinal injury centres in Sheffield and Middlesbrough, the study aims to pave the way for a wider, affordable rehabilitation programme across the NHS.

Key takeaways

  • Tests whether early arm-bike exercise helps improve torso control and balance after a spinal cord injury.
  • Designed for adults who had a neck or upper back spinal injury within the past two months.
  • Involves moderate arm cycling for 20 to 30 minutes a day, five days a week, for eight weeks.
  • Compares arm-bike training alongside standard NHS care against standard care alone.
  • Participation is entirely voluntary and does not alter your regular NHS treatment plan.

Who may be eligible?

This trial is open to adults aged 18 and over who have had a spinal cord injury in the neck or upper back within the last two months. The injury must be 'incomplete', meaning that some feeling or sensation remains below the level of the injury.

To take part, you need to have enough movement in at least one elbow to push an arm-bike pedal. If your hand grip is weak, supportive cuffs or bandages can be used to keep your hands securely on the pedals. You must also be able to understand study information provided in English.

You cannot take part if you have ongoing shoulder instability, severe shoulder pain, or pressure sores (ulcers). The study is also not suitable for people who experience severe dizziness or blood pressure drops when sitting upright, or for anyone who is pregnant.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you aged 18 or older?
  2. Did your spinal cord injury occur within the last two months?
  3. Is your injury located in your neck or upper back?
  4. Do you still have some sensation or feeling below the level of your injury?
  5. Can you move your elbow to turn an arm-cycle pedal?
  6. Are your shoulders free from ongoing dislocation or severe pain?
Answer every question to see your result.

What does participation involve?

Taking part lasts for eight weeks while you are staying in a specialist spinal rehabilitation unit. Participants are placed into one of two groups by chance (similar to tossing a coin). One group receives standard NHS rehabilitation care alone, while the other group receives standard care plus arm-crank exercise sessions. Training takes place five days a week, starting at 20 minutes per day and building up to 30 minutes at a comfortable, moderate pace. Participants wear a fitness watch to track their exercise time. No new drugs or invasive procedures are involved. Before the study begins and at the end of the eight weeks, researchers will test your arm strength, balance, trunk muscle control, and day-to-day wellbeing.

Potential risks and benefits

Potential benefits include improved arm strength, better sitting stability, and taking an active role in research that could improve future care for people with spinal injuries. The main risk is mild muscle soreness, stiffness, or tiredness in your arms and shoulders, similar to the feeling after starting a new exercise routine. The research team will guide you through warm-up and cool-down exercises to keep discomfort to a minimum. Taking part is completely voluntary, and choosing not to join or deciding to leave the study at any time will not affect your standard NHS care.

Locations (2)

  • Sheffield Teaching Hospitals NHS Foundation Trust
    City only
    Sheffield, England
  • The James Cook University Hospital
    Approximate
    Middlesbrough, England

Common questions

What is an arm-crank exercise?

It involves using your arms to turn pedals on a small, stationary machine, similar to riding a bicycle with your hands.

Do I need good hand grip to take part?

No. As long as you can bend and straighten your elbow, the team can use special straps or bandages to hold your hands comfortably on the pedals.

Will this replace my usual NHS therapy?

No. The arm-bike training is designed to take place alongside your usual NHS rehabilitation, not replace it.

Can I choose which group I am in?

No. A computer allocates participants by chance to ensure the study results are fair and unbiased.

Where is the study taking place?

The study is organised by the University of Birmingham and involves spinal injury rehabilitation units in Sheffield and Middlesbrough.

How to find out more

Shin-Yi Chloe Chiou

Always speak to your GP or specialist before deciding to take part in a study.

Discussion

Community discussion

Powered by our forum at community.patient.info. Please be respectful — this is not medical advice.