RecruitingOBSERVATIONAL

Ureteral Stent Exchange Abstention in Urinary Tract Infections

This study is about people who have a 'ureteral stent' – a small tube placed in their urinary system, often after kidney stone treatment or other conditions. Sometimes, these stents can lead to urinary tract infections (UTIs). In 2020, experts in France created new advice (guidelines) on how best to prevent, diagnose, and treat these stent-related UTIs. Before these guidelines, doctors weren't sure if they needed to always change the stent when someone got an infection. This study wants to compare two groups of patients: those treated for a UTI before the new guidelines were introduced, and those treated after. The aim is to find out if the new guidelines help reduce the chance of the urine infection returning.

At a glance

Status

Recruiting

Sponsor

Central Hospital, Nancy, France

Enrolment target

300

Start

01 Jul 2024

Estimated completion

01 Sep 2025

Urinary Tract Infections Urinary Catheterization

What is this study about?

You might have a small tube called a ureteral stent placed in your urinary system, often to help urine flow from your kidney to your bladder, perhaps after an operation or for kidney stones. Sometimes, having one of these stents can make you more likely to get a urinary tract infection (UTI). Doctors and experts are always looking for the best ways to treat these infections and stop them from coming back.

In 2020, a group of expert doctors from France put together new, detailed advice on how to prevent, find, and treat these infections specifically when someone has a ureteral stent. One of the big questions they faced was whether the stent always needed to be changed when there was an infection, as there wasn't clear evidence to say for sure. This new advice has hopefully given doctors a clearer path to follow.

This study wants to check if these new guidelines are making a difference. Researchers are comparing information from patients who had a ureteral stent UTI before the new guidelines were put in place, with patients who had one after. They want to see if patients treated under the new guidelines are less likely to have their infection come back. This will help doctors understand the most effective ways to look after people with stents who get UTIs.

Key takeaways

This study compares different approaches to treating urinary tract infections in patients with ureteral stents.
It evaluates new guidelines from French experts to see if they reduce repeat infections.
The research looks at existing patient records, not new treatments.
Findings could improve future care for people with stents and UTIs.
No active patient participation is required for this records-based study.

Who may be eligible?

This study is looking for information from people who have had a tube called a ureteral stent in their body and have also had a urinary tract infection (UTI).

If you have a certain type of urinary system where your bladder has been changed using a part of your bowel (called an ileal conduit), you wouldn't be included in this study. Also, if you've already had more than one UTI during the time the study is collecting information, you wouldn't be included for further analysis during that period. Finally, if you've previously said you don't want your health information used for research, then information about you wouldn't be part of this study.

The study includes people of all ages and both men and women. It's important to remember that this study is looking at existing patient information, not asking new patients to participate directly in a trial involving different treatments.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Have you ever had a ureteral stent?
Did you also have a confirmed or suspected urinary tract infection while the stent was in?
Do you *not* have an ileal conduit (a specific type of diverted urinary system)?
Have you *not* had multiple UTIs in a very short period (which would exclude you from how your records are used)?
Have you *not* previously objected to your medical records being used for research?

Answer every question to see your result.

What does participation involve?

This study isn't about you actively taking a new medication or attending extra appointments. Instead, researchers are looking at existing medical records and information from patients who have already been treated for urinary tract infections with a ureteral stent in place. They will be comparing anonymous details about the type of infection, the treatment given, and whether the infection returned. You would not need to do anything extra if your past medical records were included; your personal information would be kept private.

Potential risks and benefits

Since this study involves looking at existing, anonymised patient records, there are no direct physical risks to you, as you wouldn't be receiving new treatments or undergoing extra tests. The main benefit is that the results could help doctors improve how they treat urinary tract infections in people with ureteral stents in the future, potentially leading to fewer infections coming back. You always have the right to decline permission for your medical records to be used in research, and this would not affect your medical care in any way.

Locations (1)

Nancy university hospital
Verified postcode
Nancy, France· Recruiting

Common questions

What is a ureteral stent?

It's a small, flexible tube placed inside the urinary system to help urine flow from the kidney to the bladder, often when there's a blockage.

What is a UTI?

A UTI, or Urinary Tract Infection, is an infection in any part of your urinary system, like your bladder or kidneys.

Are they giving new treatments in this study?

No, this study is looking back at how people were already treated, not testing new medications or procedures.

Will my doctors know if I'm part of this study?

Your doctors won't be involved in the study itself, but if your medical records meet the study criteria, anonymised information might be used. Your care won't change.

How will this study help patients?

It aims to find out the best ways to treat urine infections in people with stents, which could lead to better care and fewer repeat infections for future patients.

How to find out more

Benjamin Lefevre, M.D. PhD

b.lefevre@chru-nancy.fr +33383154097 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.