How long does it take for 30 mg of Mirtazapine to take effect
Posted , 70 users are following.
I have just had my medication increased from 15 mg to 30 mg. When I started taking the 15 mg it literally started working the next day. I am now into my sixth day of 30 mg and I am feeling worse. I would appreciate it if someone could give me their experience with this medication.
1 like, 115 replies
stuarto
Posted
It is one of the faster acting meds of its type but that is meaning upto a therapeutic level side effects differ for everyone. I would try 22.5mg (one and a half 15mg) if you are struggling.
Mention to your Doc that doubling up isn't agreeing with you.
Stu.
michael03767 stuarto
Posted
patricia85842
Posted
3sillykidsnadog
Posted
jacqueline59667
Posted
stuarto
Posted
People react and titrate differently to minimise side effects.
E.g The best response dose for Amitriptyline can be 200mg, but if I had jumped from 75mg to that initially it would have probably comatosed me.
Slow and steady as prevention is better than cure. Glad it does what you need it to do that is the aim for us all in the end.
Stu.
Maizie
Edited
Hang in there it can take up to 10 days for u to feel the benefits of the 30mg
So I wouldn't do anything for while, just know u will see the light at the end of the tunnel soon.
Best Luck
Maizie
Zerodark Maizie
Posted
patricia85842
Posted
Maizie
Posted
... It will Improve ..... Positive thinking helps too
Best of Luck
Maizie
jacqueline59667
Posted
jane96525
Posted
Sorry to hear about your difficulties with Mirtazapine - its good to share experiences on a site like this, so you dont feel quite so alone when its tough going. From my own experience, 15 mgs had a nice sedating effect, whilst upping it to 30mgs had a more 'activating' reaction and has been extremely hard - Im on week 13 now and know I shall be on it for a further 5 months.
I took it two years ago and it worked well for me then. (but only felt better after I had been on 30mgs for about 8 weeks) During the initial weeks I felt jittery, hyper, irritated and then ready for bed by 7pm. Someone compared its effect to throwing snowballs at a wall - a little bit more snow sticks each time. A good analogy.
Basically, there dont seem to be any wonder cures for depre ssion out there! Not yet anyway. Doubtless in 10 years there will be better drugs available......(not much help now I know) So I should hang in there, believe it will work for you if not immediately but gradually, and try to keep busy when you feel crap. Any form of exercise is good. whatever you feel up to.
None of us are doctors though, so although its been incredibly good reading other peoples experiences, I would beware changing anything without first talking to your GP or another qualified doctor.
There is light at the end of the tunnel!
pauline23944 jane96525
Posted
Hi Jane
im on 30mg Mirtazapine for anxiety and depression-I've been on 30mg for six weeks and it's been so hard-15mg did nothing for me.
im tempted to give up because of the breakthrough anxiety and crying spells but I'm inspired by your post.i guess speed of response is not the same for everyone and I'm hoping that I can make the 8 week mark and feel some real benefit.
Are you still taking Mirtazapine and if not how long were you on it?
Thank you
patricia85842
Edited
It stopped working in 2012 and GP has prescribed various meds since then mostly SSRIs. They certainly don't work for me. I am now into my seventh day of 30 mg Mirtazapine so I am keeping my finger crossed.
vixxxen222 patricia85842
Edited
seems to be very popular for doctors to be doing actually.
the first week on 15mg I , like you, felt the changes immediately! I was curious why the increase would be needed and my doc told me because I am suffering anxiety and depression and insomnia.
the 15mg is usually only perscribed for ppl with sleep issues.
that being said, I have gone the full week on 30mg, this week will be my 3rd week on Mirt, and my 2nd week at 30mg.
the feelings I have are quite different than when I was on the 15mg. no doubt about it, ...the 30mg are hard at work in there lol.
my doc wants to keep me on it for 9 months , and so I am going to hang in there and see how it goes. I have never taken AD before, this is the first for me.
as I have always ignored ther fact that I have problems. Going to a doc and asking for help was a tough one for me , but whatever, I did it and here we are.
Now, ...my anxiety is very much under control.... I get fidgety sometimes but not panicy or anxiety...that is a bonus.
Its the insomnia that is the hardest one for me now. I take OTC sleeping aids, and they knock me right out, but I believe the Mirt is waking me up numerous times throughout the night . 5 or 6 times atleast. Very upsetting to me, but I try to control my frustration and drift back to sleep , which is working.
When I wake up in the morning there is no groggy feelings at all....I AM READY TO GO lol.
I believe the Mirt has me all revved up as soon as I open my eyes . which I do like because I am usually a person who feels drained after about 2 hours of waking up. but I do not feel that anymore.
I try not to assess every aspect of what I am feeling...it can get very deep if u know what I mean. I am trying to make the best of the good that I have when I get up every day,
I also have 3 daughters at home that keep me busy, which is a bonus.
I hope this helps you not feel like your alone...I am a new one to this as well, and just reading other peoples experiences have helped me alot in getting a good perspective on Mirt.
Good Luck to you
jan88737 vixxxen222
Posted
could you please let me know which OTC medecines you use for sleep ?
Garabeca vixxxen222
Posted
Hi,
I know i am replying to this after 5 years, i just read your post, i actually subscribed just to reply to you. Something raised my attention in your post in that mirtazapine made you wake up very often which is (usually) unusual. It might be that it's case by case and it's affecting you differenly but i also have another theory. Mirtazapine is known to increase vivid dreams. Vivid dreams occur during REM sleep. REM sleep is more frequent and pronounced while treated with Mirtazapine. My theory is the following: Sleep Apnea is a condition where you wake up continuously during the night because of obstructions (think snoring that leads to blockage of the airways) and so the brain repetitively wakes you up to resume breathing. Most of the time you will not remember the awakenings. Sleep apneasd is notorious for being much more severe during REM sleep because it is during that sleep cycle that the airways collapse the most. What raised a flag in your post is that: 1- you wake up more frequently with mirtazapine (which shouldn't really happen) and that 2- Mirtazapine increases REM sleep (and dreaming) by a lot where if you are prone to apneas, it would lead you to wake up more often. If i put 1 and 2 together it might lead to a possibility that you are suffering from sleep apnea and it wouldn't hurt to investigate that. Perhaps your partner could tell if you are snoring and stop breathing (between 10 seconds up to a minute at a time) only to resume breathing in a struggle. If you don't have anyone to observe you while sleeping, you can voice record yourself with the memo app on your smart phone. ( i did that and heard myself struggling to breathe countless times during the night). Or you could just go see a doctor and ask if you could do the sleep apnea test because you are suspecting you might have it. By the way, i have very severe sleep apnea ( i stop breathing 89 times an hour) and i never remembered waking up most of the time but only remembered waking up 5-6 times night ( when it was actually 89 times an hour! i didnt suspect sleep apnea at all, until the sleep study revealed it and i was shocked (and so was my doctor) it was very severe. Just a suggestion for you to maybe look into that.
Cheers !!
Carl