30mg Mirtazepine

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Hi, i've just been prescribed 30mg of Mirt by my doctor, as i have anxiety and which has led to anorexia through loss of appetite, but i'm not sure if it will help. I think the doctor has given me this to increase my appetite and give me weight gain to gain the 16lbs i have lost in 2 months.

I must mention that i also have an underactive thyroid too. I am seeing a psychotherapist for my anxiety problems.

Will Mirt/Zispin help me put the weight on at all ? Desperate to regain the weight i have lost.

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9 Replies

  • Posted

    Hi Dave. Nobody can say for sure how it will affect you. Many people do gain weight using this drug so may well do. Best wishes to you Tony
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  • Posted

    It may well help Dave.

    Given the symptoms you've described, I am not surprised that your doctor has prescribed Mirtazapine.

    I think I'm right in saying that Mirtazapine was originally developed to help people with anorexia and it contains an appetite stimulant. It's in a whole different antidepressant class from SSRI's like Citalopram or Fluxotine or tricyclics like Amitriptyline.

    Many people find weight gain to be an unwanted side effect of this medication!

    It is also an antihistamine and as a result is sedatory. I take it in conjunction with Sertraline. Without Mirtazapine, I can't and don't sleep.

    You need to give the drug three or four weeks to allow for the \"theraputic lag\" and start seeing the benefits of it.

    Stay in touch with your doctor and speak to him if you have any concerns at all.

    Good luck and best regards.

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  • Posted

    Hi, I thought i was the only one to take 2 antidepressants every time i go to pick my prescription up the chemist always asks \"have you taken these before\" it was prescribed by a psychiatric dr, I take 40mg seroxat 30mg mirt ,3x5mg diazapine, propanolol and prescription strength co-codamol for arthritis, and yes I have put on a lot of weight, but still have some anxiety and trying to reduce the seroxat.

    I shop out of town so i wont bump into people i know, and am desperate for the hairdressers I just cannot sit still and end up just wanting to get out of there , although today i went for an eye test and felt ok. my problem is that i go all blotchy around my neck and feel hot and i can see that in the mirror at the hairdressers, have tried a home hairdresser where i cannot see it for myself but couldnt sit still long enough for her to finish, if only i could concur this.

    At 53 with waist lenght hair i feel and look like a old hag, and think people see me me as Jean out of Eastenders a quivering no confidence wreck.

    Take Care

    Colette x

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  • Posted


    I have put on weight from Mirtazapine. Iv gone up a dress size from being on it only 2 weeks. It makes me crave sugary foods so i guess my plan now is to hit the gym as soon as.

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  • Posted

    Although i have one question...

    Most people are started off on 15mg of mirt, i know it's more sedating and more side effects on a lower dose. Whereas 30mg is not so sedating, is 30mg an okay starting dose?

    The increased appetite and weight gain is something i can really do with. Hopefully it does work and also lifts my mood.

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  • Posted

    I'd say 15mg would be the normal starting dose, see how you react to the drug and then build up to 30 mg. But if your doctor has suggested you start on 30mg I imagine he has his reasons.

    My own view would be to speak to him and voice your concerns. If you like, suggest to him that you start on 15mg and see how you are feeling after a week, then build up to 30 mg if all is well. I imagine he will want to see you shortly anyway having started you on an Antidepressant drug to monitor your progress.

    The maximum theraputic dose of Mirtazapine normally prescribed is 45mg (albeit you can go higher under medical supervision) which is why I think 15mg might be an easier start for you.

    There's no substitute for proper, informed medical opinion though so if you're at all unsure or concerned then speak to your doc.


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  • Posted

    The reason he wants me to start on 30mg is to get more of the AD into my system quicker. However my consultant psychiatrist didn't want to medicate me at all and that i will overcome my anxiety, i think these people don't understand really, they don't live with you to experience it.

    I see my doctor tomorrow, and i will talk about it to him, he did say you can start on 15 if i wanted to, but i don't want to be sedated for hours on end.

    30mg looks to be less sedating.

    Will i experience stomach ache if i am eating much more than i am just now with an increased appetite?

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  • Posted

    I guess I've got into the habit of taking Mirtazapine half an hour before I want to go to bed. It pretty much then lets me get a decent eight hours sleep in, which is what I need.

    Having woken up, I don't then feel especially dozy during in the day [i:78c29771aa]but [/i:78c29771aa]I am also taking Sertraline and when I was on that on it's own I was hyper and couldn't sleep at all. Hence why the psychiatrist added back Mirtazapine to let me sleep. So it may well be the drug combination that is giving me a sleep/awake cycle

    Stomach ache is not my experience of Mirtazapine but increased appetite certainly is! When I was first on Mirtazapine in isolation about two years ago I put on about two stone in two months. I've got that weight off now but given you are looking to put weight back on hopefully the drug will help you do that.

    Good luck!

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  • Posted

    Weight gain is about the only thing Mirtazapine is guaranteed to give you.

    I cycle 100 miles a week and run 20 miles,and still put on nearly 2 stone in 6 months.For the extra 2 hours of sleep I get now and again when I take it-i don't think it's worth it.

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