4 months swollen one knee - please advice

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My small niece, she is 2 years old, and her left knee is swollen for the last 4 months, still now we don't have any exact diagnosis. 2 times did knee fluid aspiration, and several times ultrasound, and X-rays but couldn't found any significant except some inflammation on that knee.

Last month, took several blood tests including - CPR, WBC, ASLO, ESR - and they were on normal range, however, ANA it was - 83.8

Could somebody please tell me, what might be the issue? and I'm worried about the result of ANA, and does it alone can indicate that it could be indicator of auto immune disease?

Thanks.

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