4th week on 100 mg still struggling badly

Posted , 8 users are following.


I would be interested in success stories as Ive been struggling for so long now. Ive been on 100mg for 3 weeks and 2 days, yesterday I had my first good day, started to be hopeful, I felt about 70-80% good, but today I feel awful again, intrusive thoughts, anxiety is high, very low mood, very hopeless again, and feeling sick. Cant do anything just laying around again.

Just wondering if anybody felt this way and then had success on this med please? Is it worth to wait or its just time wasting, being in doubt killing me.

Thanks for reading it,

Kind Regards,


0 likes, 10 replies

10 Replies

  • Edited

    PLEASE give it more time . I was exactly the same and its really hard after a good day and then a another bad to feel you are making progress.

    The goods days, as I read on this forum start getting more and more .

    I have taken Sertraline for 10 wks . I'm still wobbly but SO much better .

    Keep going , dont despair!

  • Edited

    Did you have intrusive thoughts before taking it, made mine worse and made me very depressed so had come off it. Hope you get some positive replies!

  • Edited

    I have been on ZOLOFT for 4 years. 50 mg but was not helping 4 months ago. No side effects at first and took 3 weeks to get me to normal. Felt good all along.

    Anxiety creeped in 4 months ago and I upped the dose to 75 mg and than to 100 mg and later to 125 mg for 6 weeks. Did feel a few days better but overall felt lousy.

    This was all with my physician's consent. 3 days back I went on 150 mg and am waiting to feel better. I am hopeful that it should start working. I do have a few good days,

    If no change than I will see my physician and she maybe increase my dose.

    This process is slow and one has to be patient. Side effects are different for different people and time also varies.

    You will have be patient and persistent.

    Hope you feel better and you must stay in touch with your physician.

  • Edited

    Hi Bulldozer,

    I was on 100mg and it got rid of my intrusive thoughts and low mood after about 6 weeks. Unfortunately, I noticed I developed a tremor and internal shaking. My psychiatrist wasn't sure if it was the drugs of the anxiety but has recommended switching to Vortioxetine which I am going to start this week.



  • Edited

    Yes, exactly what Susanne said, please give it more time, it's a real roller coaster with good days then bad days - I went through this caring for my daughter - it took her 6 weeks to start having good days but then she had some awful ones mixed in. Pretty soon her good days outweighed her bad days - at 13 weeks she was her old self again. She eventually was able to go off the meds and has been thriving ever since.

    Please read this post by Kate in this forum, it gave me SO much hope when I was struggling to care for my daughter and was worried the meds wouldnt' work:


  • Edited

    Wait 3 more weeks

    If it doesn't get better, change to another SSRI or SNRI.

    SERTRALINE can cause shaking, anxiety and agitation more than others SSRIs although this is not common. Less than 10% of people experience anxiety and agitation, but if it does not get better at week 8, change to another medication.

    All SSRIs can cause agitation and anxiety, but SERTRALINE is interesting: for some people it's the best anti-anxiety medication on earth, while for less than 10% it's one of the most activating medication out there.

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