4th week on 50mg

sertraline worked for me over 20 years then pooped out.

Are you still taking Mirt?

yes 3 days 15mg and pristiq 14 days at 50mgs

Hi Sue, is your depression improving?

yes it has, I am still not happy but I am not sitting on a bus with tears in my eyes for no good reason, although if you live in the uk using public transport can make people cry 🤔, I know this medication is better suited to me then the last one was, just a question of finding right dose and waiting

That's good. I have been on Venlafaxine for 3 months with very minimal improvements and just didn't feel right..hazy head most of the time, could not sleep at all without other meds for sleep and developed severe tinnitus. Sert at least is not making my head foggy and I don't feel tired all the time and can sleep in my own. Now it's just waiting game and the right dose.

stay strong ala and I am sure by christmas we will both be dancing on tables, or at least doing a little shuffle round the tree x

That would be great to feel better by then... I saw my doc and she would like me to continue on 50mg for another 3 weeks and slowly wean off Venlafaxine. If I feel a bit better hit still not fully, she will increase my dose to 100.I hope you are also improving! x

glad you are feeling a bit better, baby steps and you will get there. your dr seems to be one if the sensible ones in understanding about switching, I had a fairly good day yesterday, lets see what today brings, have had lower back pain last couple of days, do not know if it its meds or not, we do seem to blame anything and everything we get on the meds when it maybe just life. have a good day and try and be positive x

Hi Sue, my mood was slightly better yest afternoon so it helps to lessen anxiety and sleep better. However this am I feel very tensed and my mood is very low. My mornings are still tricky because I have been ill for a food while and I worry will I ever recover and what if my depression is treatment resistant... I think once my mood picks up more, these thoughts will go away. I am glad you are doing ok. x

What was the side effects when you first started sertaline, thank you do you get bad dreams

if you are having glimmers of feeling a bit better in the afternoon/ evening then I would not worry about being resistant, there is a patient in my surgery and she is med resistant and none of the standard ad's worked for her she had 24/7 symptoms. mornings are always the worse for a lot of people, they were for me but it is not an indication on how the rest of day will be x

vivid, weird dreams but not bad or scary do not worry about them they will go away, if you take your meds at night maybe switch time you take them, may help?

Dear Sue,

could use some advice. i was treated with sertraline for 23 and it worked great for severe anxiety for 23 years than pooped out a year ago. tried prozac for 8 weeks and lexapro for 4 weeks now on pristiq for 2 weeks at 50mgs and remeron 15 for sleep I am worried of being drug resistant. i take .5 klonopin in the am because the anxiety is worse in the am. how long is a fair trial to work. Do you know anyone who has tried ketamine drips for bad anxiety. i do see a psychiatrist for therapy and drugs and i know she would not approve of ketamine

Thank you Sue! You seem like you know what you are talking about... I don't have any side effects now in Sert so I hope it's a good sign! xxx

how long have you been on sertraline now? I tried it a second time after it pooped out but didn't work now 2 weeks on pristiq and 15 0n mirtazapine. are you getting anxiety at 4 weeks in. does it take 8 weeks

hi lynne, let me first say I have no personal experience with any of the drugs you have been given. all I know is that prozac and lexapro are ssri and pristiq is a ssnri, which means, as I am sure you know, they react on different receptors in your brain. you have had a lot of switching over the last few weeks so if you are getting any relief from pristiq, even if it is fleeting, I would say give it a few more weeks , time to let things settle down, if after that you still do not feel like you have any improvement at all then speak to you dr. I would not worry about being drug resistent at this stage because sertraline has worked in the past, it may just mean your body has got used to it and you need something different hence the ssnri as opposed to a ssri. as regards to the ketamine, it is an illegal club drug in the uk so am with your medical people on this one do not mess with it but at the end of the day you are a grown up, your life, your choice just be very careful x

yes it means that the meds are settling in and will now start doing their work. onwards and upwards

can it take 8 to 10 weeks to work. did you have horrible anxiety. i calms down later in the day. yesterday i felt better. did you take benzos to help with the anxiety.

i think most of the problem is i don't give them enough time to work and change to quickly like four weeks this one i will give 3 months. i took the gene sight test and this one was reccommanded

Hi Lynn,

It's my 4th week on Sert. I have started feeling better in the afternoons and evenings but I still have a way to go... I am also still on Venlafaxine 75 as I am weaning of 225mg dose. I should be off Ven in 3 weeks and if my mood has improved on SERT 50 but there is still room for improvement, them will go up to 100. I have also been off Mirtazepine for a month now and just last week I started sleeping on my own after 6 months... I have not been using any antihistamines or Xanax. My anxiety is more of a worry about being depressed so I really hope Sert will be my med!

my problem is anxiety and not so much depression. hope pristiq works. i still need to take klonopin in the am.

did you take xanax at all during the day for anxiety,