Aggressive/ short fuse with Mirtazapine

Posted , 5 users are following.


Has anyone else had a ‘short fuse’ or aggression whilst taking Mirtazapine? 

I am finding that I have no patience and losing my cool more than usual. I am taking 15mg with 150mg venlafaxine ER.

Many thanks 


0 likes, 10 replies

10 Replies

  • Posted

    Yes me was in them 3 months and I had a nasty streak which is not like me at all
    • Posted

      That and the eating situation a d I felt groggy and very tired all day
    • Posted

      I feel the same but it’s only been 2 weeks. Do you feel better for getingn off them or has it made you worse? 
  • Posted

    I’ve dropped from 30 to 15mg but yes made me incredibly irritable the smallest things - someone rustling paper loudly - a door closing a bit too abruptly and I’d explode in a rage - it really isn’t my character at all and it’s been going on too long - I’m making moves to withdraw as comfortably as poss - if that is possible! 

  • Posted

    My partner has got this as well and becomes unbearable especially as she drinks and has mental health issues. They should definitely do more tests on mirtazipin if u ask me.
  • Posted

    I was irritable and developed explosive temper over the smallest occurrences .

    Not my usual character at all - so decided to withdraw - I’ve posted about my experience to date - I feel for you it’s awful 

    • Posted

      Thanks Rob,

      I don’t seem as bad on 15mg at the moment but don’t seem to be doing anything other than make me sleepy. 

      I take 150mg of venlafaxine too and this has always worked for me in the past but GP is reluctant to increase this 

    • Posted

      Re sleepiness I was advised by my gp that the lower doses make you “sleepier “ - I went from 15mg to 30mg on his advice - everything just got worse - I was totally devoid of energy and lethargic most of the day - app some say the 45mg dose can stop the tiredness - I wasn’t prepared to there to find out tbh!

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