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I have had Barrets for many years on various medications and for about 2 years I have been on Esomeprazole 20mg twice a day and 300mg Zantac once daily at night. This worked well for me but now Zantac has been withdrawn due to cancer causing concerns. My Doctor has suggested doubling up on the Esomeprazole, so 40mg twice a day which is the max subscribable dose. I tried sticking to 20mg twice a day but symptoms have returned, particularly nausea. I doubled up on the night dose last night and had a better nights sleep, but I know this PPI like others has side effects particularly the way it effects mineral and vitamin balance and kidney damage.
Alternative H2 blockers just don't appear to be as effective as Zantac. Have any of you been down this route and any advice would be great.
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