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I hacve been taking cocodamol and ibruprofen for severe joint pain. Sometimes it is really bad that I can hardly move. I saw my GP yesterday and he prescribed Amitriptyline to be taken at night incrasing gradually to 50mg. I was told this was once used as an ani depressant, and on reading the leaflet inside it terrified me as it says you can get sucidal feelings. Just wondered if anyone else has been on this drug for pain and how they coped with it.



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  • Posted

    Amitriptyline is prescribed for nerve pain so presumably the doctor suspects that this is the cause of your pain.

    I was diagnosed with hip OA years ago but I've never had any pain. But around a year ago I tweaked a muscle doing deadlifts and after a couple of 'retweaks' I ended up in incontrollable sciatic type pain. I couldn't sleep, I was on on cocodimol, diazipam (muscle relaxant), tramadol, diclofenec - all at the highest dose and it wasn't touching the pain.

    Finally I got onto amitriptyline and that eventually got the pain under control. I stopped taking all the pain relief and after about 6 months I stopped taking the amitriptyline and now I'm pain free and back to my active lifestyle. There was also a psychological element to the pain with me (the pain was very real, but I'd got into that 'chronic pain sufferer' cycle where the nervous system over-reacts to pain singals - if that's a possiblity let me know and I'll tell you how I solved that one!).

    I was lucky - aside from feeling drowsy for the first few days and a bit of a dry mouth at night I had zero side-effects. Most drugs **CAN** have side-effects, but with this on I think most that you do get wear off. You build up the dose gradually to let your body adapt. I built up to 50mg and took that for a few months.

    Have a google search for the terms "amitriptyline pain concern" that will bring up an article on the Pain Concern website that should put your mind at rest.

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    • Posted

      I was very interested to read your reference to 'chronic pain sufferer' cycle.  I hadn't heard of this before but it struck a chord with me.  I would love to know what you did to address this and if you can point me to any further helpful info.  I've been experiencing chronic tension headaches and migraines very frequently for several years now and my GP has just suggested amitriptyline as a preventative measure.  I'm not too keen on taking a prescription drug and the potential side effects, but I'm also not enjoying my life with this chronic pain!  
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  • Posted

    Hi Louisa

    I dont take this one....was offered it but it clashed with another drug I was taking but I know a lot of people that do take it.

    The only problem I've come across from talking to them is a dry mouth and sometimes drowsieness when its given as a muscle relaxant. They find they have to take it about 7pm for them not to feel really drowsy in the mornings. They have tried different times but definitely not last thing LOL



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  • Posted


    I was taking it until I was getting migraines that would not go away. It helped me with the pain. Anti depressants are often prescribed for pain as mood sets the tone for cortisol release a hormone which causes pain. The receptors in the brain pick up anti depressant meds and controls cortisol release in the brain the pain causing hormone. 

    A merry go round if u will effect go on without antidepressants. Pain causes depression, depression & pain cause the hormone cortisol release...and round we go. 

    Antidepressants do help stop the pattern in the brain and there r many types on the market. Try not to put to much weight on the side effects give it a try. It could help give u better pain relief. 

    GOOD LUCK exclaimbiggrin

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  • Posted

    Hello Louisa,

    I have been on amitriptyline for a few months now, to help with pain and sleeplessness. Have gradually worked my way up to 40mg, doctor said I can go up to 75gm. I find it helps with the sleep, in fact I have to take it at 6pm otherwise I could sleep for most of the next day! It does releive some of the pain, but not all. It does not stop me from sleeping, gradually builds up during the day, if I have been quite active, in which case I take ibuprofen. I have not had any suicidal feelings. Hope this helps.

    Take care Anne

    Hope this he

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