Amitriptyline - How long does it take to work?

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I’ve been on amitriptyline for 5 weeks on 20mg for pressure/tension headaches but still suffering. How long should they take to work? Should I switch to propranolol instead? 

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  • Posted

    It should take effect within a few days, propranolol slows down the heart so it may work better for if your headaches are to do with blood pressure, have you tried a more physical treatment like, accupressure? Ill look more into it if you like
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    • Posted

      Have you had any more experience with amitriptyline? They are meant to work for pressure headaches so unsure on why they are not working yet. I was on propranolol before for migraine headaches which seemed to work but unsure whether they will work for a more tension type feeling
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  • Posted

    I would give it a little more time. My neurologist also has me taking 400mg of magnesium and 200mg B2 every day.I might get 1 headache a week but the severity seems to have lessened
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  • Posted

    Hello,

    I tried 25mg of amitriptyline for awhile (6 weeks maybe) as a migraine preventative and to help with tension headaches + anxiety.

    Honestly, they made the problems worse for me. That on top of the tiredness and and zombie like feeling, migraines were a lot worse and more frequent. When a migraine struck, it crippled me whereas beforehand, I could kinda get through the day with mid-level migraines.

    I have been moved to 80mg propranolol and I have to say, so far a lot better. Almost relief the next day, maybe 60% less severe.

    My migraines are definitely blood pressure related due to anxiety.

    I have been switched to Sertraline to go with the propranolol but not yet started.

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  • Posted

    You should have had some results by now, if your going to switch seek advice you may need to reduce the ami slowly to avoid the withdrawal type symptoms x
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