Amitriptyline side effects

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I was prescribed 10mg Amitriptyline per night for very bad headaches related to a neck injury. That has now healed and I stopped taking the drug about 10 days ago. I've experienced bruising and diarrhea which I believe are know side effects of the drug but also some lower GI bleeding which I written about elsewhere. These things are under investigation - doctors saying suspected diverticular inflammation - but wondering of the Amitriptyline could have had something to do with it as bleeding is also listed as a sided effect. Any thoughts?

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  • Posted

    How long were u on Amitriptyline and did you gradually wean off this drug? Curious, as I have been prescribed this recently as well, 10 mg at bedtime.
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    • Posted

      Only about six weeks while the neck injury healed. The doc had said this was a low dose to work as a painkiller (rather than the higher doses when used as an anti-depressant) I didn't think to wean. At first, concerned as it made me feel dozy in the morning, I was cutting the 10mg tab in half but 5mg wasn't enough to deal with the pain whereas 10mg was.
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    • Posted

      Yes, it does make you drowsy. I'm battling that now. No bleeding though and yes, bruising and bleeding are some of the serious side effects but I am glad that you are off it and hopefully the bleeding will resolve itself now. I was on another type of pill which bleeding was listed as a side effect. I did experience the bleeding, not significant, but still worrisome as you can imagine. I stopped the drug and the bleeding stopped as well. Pretty scary stuff but I am glad your dr is ruling out anything serious. I hope you feel better soon. I, too, suffer from neck pain due to a previous injury, so I feel for you. Take care smile 
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    • Posted

      My doc said to take the amitriptyline two hours before bedtime to counteract the morning drowsiness. As I don't have a particular time for going to bed or if I had been out for the evening, that wasn't always possible. Even if I did take it two hours before, I still felt zombie-like come morning. But that did wear off after a couple of weeks. Sadly, my bleeding is significant and so it may have another cause. Diagnostics scheduled for Saturday so fingers crossed.
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