Amitriptyline starting dose for trapped nerve.

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I have MS, and what liitle distance i can still walk, it'st a strange Frankenstein type shuffle, resulting in damage to my spine, and a pelvic tilt. The past six months or so the pain in my right hip has worsened, then becoming intense pain in my right buttock, outside right calf, and right ankle. Physio is convinced I've a trapped nerve, caused by spinal problem (herniated disc he thinks) I now can hardly put any weight on my right side as the pain causes my leg to contract. Results if xrays not with GP yet. He has put me straight away onto 25mg of Amitriptyline at night. Is this a too high starting dose? Feeling like a zombie in the morning, and after seven days no pain relief at all. Co-codamol doesn't work for me, and Tramadol likewise had no effect. I'd really appreciate your thoughts. Many thanks.

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  • Posted

    Hello cat. I started on 20mgs but I think 25mgs is a dose patients do start taking. You'll probably start to feel less like a zombie in a week or two as your body gets used to it.
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  • Posted

    Hi cat

    Sorry to hear you have MS i take 40mg per night I started on 30 mg last April I still get the hangover effect every morning it wears off I find if take it the same time every night 8.30 and go the bed around 12am I can get a good night sleep.

    I take it for chroinc lower back pain it's the Only drug I've found that works for me

    It takes around 4-5 weeks for the drug to work

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    • Posted

      Thanks Marshall. I'm looking forward to the weeks passing, and the pain becoming manageable... success through a positive mental attitude... I hope biggrin
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  • Posted

    If you really are not coping with 25mg, your GP can give you some 10mg tabs to get used to first and then gradually ease you up until you get pain relief hopefully. If it is just intolerable or not working then DO tell the GP and they can try something else. 
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