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Second day off Amlodipine 5mg. Was on it for almost 3 weeks. Feel a huge difference except for the horrible ache in my calves. Any suggestions how to help/alleviate this? Thanks 

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    Hi Alison..I use a Revitive machine that stimulates the circulation and it works.i had problems with my calves whilst on Amlodopine ..had to be tested for D V T at one point it was so bad.i think it’s all due to Amlodopine causing relaxation of the blood vessels in the legs and also resulting in the excessive ankle swelling.i would ask your go for advice.
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    Alison, it can take a couple of weeks for side effects to resolve completely.......if they are going to!  One side effect for me was swollen and inflamed ankles which developed into a diagnosis of varicose eczema which is now permanent - with hindsight, I should not have ignored this side effect and stayed on Amlodipine as long as I did (about 4 months).  I have learned my lesson and now discontinue each new med in a couple of weeks if problems surface......which is almost

    always as I’ve turned out to be super-sensitive to drugs.  My quality of life goes out of the window on most of them so unfortunately I have to take my chances and try living with uncontrolled high BP!  I take Losartan 50mg - the only one out of about 8 different pills that doesn’t give me any discernible side effects - but it isn’t doing much, if anything, for my BP, but adding a second pill has proved disastrous each time, landing up in A&E on the latest trial!

    I agree with Elizabeth, your first port of call with your calf pain should be your GP to rule out any signs of a clot developing.  Good luck!

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