Antibiotics
Posted , 10 users are following.
this has been mentioned a few times. Why do broad spectrum antibiotics reduce inflammation and pain when there is no bacteria present.
2 likes, 47 replies
Posted , 10 users are following.
this has been mentioned a few times. Why do broad spectrum antibiotics reduce inflammation and pain when there is no bacteria present.
2 likes, 47 replies
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Cheba lyn4668
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suzanne00 Cheba
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I would assume that all benefits with non-bacterial use of antibiotics would be short-term, and that good gut bacteria would also likely be an associated causalty with use. But, it's helpful to know why it may improve LS briefly.
Morrell1951 Cheba
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Anti-Inflammatory Effects of Antibiotics
Antibiotics decrease inflammation in the vast majority of cases because clearing an infection removes the reason for the inflammation. However, a number of studies since the 1990s have contributed to the idea that some antibiotics might also directly limit or change the inflammatory response, as discussed in the December 2007 issue of “Rhinology.” Several classes of antibiotics, including the macrolides, tetracyclines and the beta-lactams, when used in certain chronic illnesses, appear to decrease inflammation in addition to their antibacterial effects. This research represents a mix of experimental and clinical studies, some performed only on cell cultures rather than patients. The antibiotics mentioned show a variety of ways they might affect the inflammatory response, including changing inflammatory cell metabolism, altering cytokines and other chemicals that stimulate and help maintain inflammation, and speeding the breakdown and removal of inflammatory cells. Any or all of these mechanisms could act to decrease inflammation.
hanny32508 lyn4668
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greg73500 lyn4668
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I have cured myself of LSC (Lichen Simplex Chronicus), which presents itself differently than LS, but is also considered a stress/immune-related and incurable skin disease. I used oral St. John's Wort to do so, without knowing in advance it might cure my condition. Later reading helped me discover that SJW had wound-healing properties, was anti-inflammatory, but most of all, that it contained a molecule called Hyperforin, known to be one of the most potent anti-microbial agents against SA (although not available in an approved prescription form).
My dermatologists never checked my LSC wounds for SA. However, I speculate that SJW may have helped my body combat such an infection, reduced inflammation, and perhaps helped repair the damaged skin barrier that would have allowed bacterias to colonize the wounds in the first place.
For reference, I suffered from LSC for 20 years, and nothing I tried in conventional or natural medicine provided a cure, until 6 weeks of oral treatment with SJW. I have now been free from all traces of LSC for over a year. All the info about skin wounds, their potential SA colonization, and SJW, is available on various scientific research sites on the Web.
hanny32508 greg73500
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greg73500 hanny32508
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Simply type PMC4085041 in your search engine if you want to learn more.
Regards,
Greg
hanny32508 greg73500
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By combining all our experiences here on this forum, a light may go up with many of us. Thanks again.
hanny32508 greg73500
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It was the staph bacteria you mentioned that caught my eye. It seems that coconut oil is doing the same, kills the same bacteria. I'm using a lot of coconut oil for lubrication and rinse with baking soda. The LS is on retreat. I have no proof of anything to be beneficial, it simply starts to show that it is beneficial.
Will have a look at your web findings. Thanks again.
greg73500 hanny32508
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I also found out that there are other interesting herbs, mainly those used in Chinese traditional medicine and containing Berberine, that might be employed to combat resistant Staph.
Finally, one of my readers on a different forum, who is currently affected by chronic eczema, decided to try SJW, but not through the systemic route I employed. She actually made herself a balm with 3 parts coconut oil and one part SJW oil, that she bought from her health food store. Her initial reaction to the first application was very encouraging. I will be looking forward to her follow-ups.
We are quite likely getting somewhere! All the best!
hanny32508 greg73500
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katie90075 greg73500
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greg73500 katie90075
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600mg/day of SJW extract is all it took to get rid of a 20 year-old disease for which all the other tricks in the book had failed miserably! The symptoms were gone in 6 weeks, and the scars in 5-6 months. I wish I would have known in advance what SJW could do for me, because I would then have bought the cream or the oil for instantaneous relief on my lesions. However, the systemic treatment did a perfect job with a little time, and did so without any side-effects either. I have now been LSC-free for almost 2-1/2 years, to the disbelief of all my doctors!
You should read about potential interactions if you are going to try SJW while taking any other medication. I was on nothing else but SJW and my perfectly ordinary diet and lifestyle.
BTW, this is not my main thread for discussing LSC and SJW... I have posts both in the Alternative and complementary medicine AND the Eczema and dermatitis forums where I discuss the subject with other patients.
Best of luck if you elect to try SJW and please keep us posted on your progress!
Greg.
katie90075 greg73500
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greg73500 katie90075
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However, please be patient with the systemic treatment (as long as you tolerate it well)... I'm convinced we are dealing with a very stubborn bacterial infection that taxes our immune systems, and getting rid of it takes time. A patient on another forum whose body was literally covered with wounds had to wait 12 weeks before experiencing any benefit, but he is now very happy to boast about a huge drop in the surface covered by the lesions, a disappearance of all the itching, and of course, the rediscovery of quality sleep. it's been a few weeks now since his latest update, and I'm hoping he will soon tell me the disease is completely gone.
Best regards.
katie90075 greg73500
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That is amazing that it cured all his wounds. I've delt with this for so long that 12 weeks is worth the wait. Thanks so much
katie90075 greg73500
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greg73500 katie90075
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Everyone reacts differently to medicine. If you are brave, go for it and take 900mg from the very start! If you wish to be conservative and to first test how your body generally responds to SJW, then start off low and increase the dosage little by little. It also depends if your LSC covers a large part of your body. In my case, the LSC only covered my lower legs below the knee, although it was very intense.
Hope this helps.
katie90075 greg73500
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I think I'll try 600.
I have it in the worst place possible. Front and back. It's runing my life. I can't even play with my kids, exercise, do normal things sometimes (most times). I used to be embarrassed by it but now I'll shout it from the roof tops if someone will give me a cure.
I think it is wonderful that you have been cured for over two years and still continue to help others. You're a good person.
Thanks again!!
greg73500 katie90075
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I wish you a very nice first weekend under SJW!
Greg.
katie90075 greg73500
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greg73500 katie90075
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Everyone reacts differently to medication, natural or conventional; but yes, I have read that St. John's Wort may cause muscle cramps just as some people claim it helps relieve them; It can also cause skin rashes, yet, it can also help remove them (as it did for my LSC, if we can call that a skin rash). It can also cause nervousness and agitation, yet it is mostly recognized to reduce such symptoms. Strange paradoxes unfortunately, but you can easily find out about known potential SJW side-effects by typing St. John's Wort side effects in your search engine.
I also hope the muscle pain you are feeling is pure coincidence, but I would obviously ask if you've already felt such cramps in the past, and could you have done any strenuous exercise in recent days that might have triggered them?
You're also mentioning that no pain killer or muscle relaxant can help, but did you indeed take any pain killers or muscle relaxants or was this just figure of speech? As mentioned, one should be careful about taking any medication at the same time as SJW, and check for possible interactions either through a health professional or a serious drug interaction website.
katie90075 greg73500
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Thank you for your response I really appreciate all the help you have been and I am going to keep trying to see if it works for me too.
greg73500 katie90075
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In theory, I think the idea of treating the disease from the inside out (with pills) probably offers better hope for a permanent cure because oil applied from the outside may not necessarily penetrate into the deeper layers of the skin. But not everyone can tolerate the systemic treatment and you have to go with what is possible. I have to admit being very lucky that absolutely everything went well in my case.
So it might be best to wait a few days for that muscle pain to disappear before trying the pills again, and perhaps at the minimum dose this time (300mg), just to see if there is indeed a connection. Hope there isn't.
Good luck!
norma54754 greg73500
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I have ordered "Hypercal" a cream containing hypercium(SJW) and calendula.
It is another trial cream for me, to sooth any irritation from LS.
If it is not a success for LS I will try using it for eczema on my foot.
katie90075 greg73500
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greg73500 norma54754
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I find it interesting that you have both LS + Eczema. The last dermatologist to have looked at my lesions told me I probably had a combination of LSC + LP. I am beginning to think that there is a link between all Lichens and all varieties of atopic skin, be it eczema, psoriasis etc.
I don't know if you have read the latest findings at the University of Michigan School of Medicine and the link between eczema and Staphylococcus Aureus, but if this discovery is correct, it certainly would explain how I got cured from LSC/LP thanks to the antibiotic and anti-inflammatory properties of SJW.
I hope the cream will provide you gret relief. Good luck!
greg73500 katie90075
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...or you might be able to dilute the original product by mixing it with a bit of olive/coconut oil. The base for most SJW oil is generally Olive Oil. I have to say it must not be easy applying anything with alcohol on an inflamed wound. Maybe the sting will also disappear with time, if the ingredients in the oil start doing their job against that inflammation.
katie90075 greg73500
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norma54754 greg73500
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I think it possible an inherited disposition is possible as I have a sister with LS and eczema and it just needs something to trigger a reaction.
In my case my thoughts are an imbalance of hormones may be the cause as both skin disorders appeared after menopause in both myself and my sister.
On asking my doctor what he thought, he didn't think it hereditary but he did thing LS and eczema are connected.
I don't expect the cream to be a miracle cure, rather it will be one that I can interchange with other suitable treatments as I think it best to alternate treatments.
If it proves to be better than my expectations then I will be thrilled.
Thanks for good wishes.
greg73500 norma54754
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If your skin barrier is damaged for any reason, be it, sunburn, hormones, age etc., it becomes fertile ground for a resistant staph infections that will cause your skin's mast cell to degranulate, liberating the histamine that causes the itch and the inflammation. According to what research has proven so far, the beauty with SJW, is that it apparently kills the resistant strains of Staph, combats inflammation, and helps repair damaged skin by reorganizing the epithelium. I have no clue if it can do that with all varieties of skin diseases/atopic skin, but it might be worth a try when someone has the ability to tolerate it and doesn't need to take medication that is on the interaction list.
Cheers!
janniey hanny32508
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hanny32508 janniey
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Due to adrenal gland problems, without medication I would be in danger of infections for sure. But since the time that I have meds for that the infections have been very much reduced. Though I wasn't so happy with the use of steroid because it does affect my delicate immune system. Sometimes a person has to choose between two bad ones. Certainly in the beginning days of my LS.
janniey hanny32508
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katie90075 greg73500
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greg73500 katie90075
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We can't post links on this forum so I'll private-message you Point you to the blog where a lady and her readers have been using SJW and commenting on it. She is in France however (I speak a few languages), so if you can't understand French, it might only be useful to see a few pictures of skin wounds healing with SJW.
Hope this helps!
norma54754 katie90075
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a tinture is too concentrated to use neat especially on already inflamed skin.
You could try making your own concentration by mixing a few drops into an oil or cream of choice rather than disguarding it.
Let your skin calm down first before attempting again.
SJW carrier oil can be obtained very reasonably from the well known internet site.(not sure if my post will get banned if I mention the name but it begins with A and ends with N).
norma54754
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I'll re-word that..discarded.
hanny32508 janniey
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I can feel when I need to use a bit of Globetasol again. It's still needed. Realizing that LS won't disappear, it is always there. It needs constant care and that's what it gets. Resulting in me being able to live fairly comfortably. I'm very careful therefore to leave 'the glob' out entirely.
norma54754 hanny32508
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Apart from poor diet, stress is as bad as anything for increased blood sugar and insulin spiking.
It only needs a stressie situation for the liver to release glucose into the blood stream and if you are already insulin ressistant or pre-diabetic it makes a difference.
Maybe you were not in a calm place run up to or around October last year unless of course you were having too much of a good time indulging yourself. lol.
dana67195 greg73500
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greg73500 dana67195
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The link should be in your mailbox in the next few minutes. Guess you'll enjoy reading her comments when she hit the 2 month milestone with SJW. As you will likely read, this is the first summer in a very long time that she was able to sunbathe, and she is now off SJW.
Cheers!
dana67195 greg73500
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hanny32508 norma54754
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