Antibiotics and PMR
Posted , 11 users are following.
I have had PMR for about 2 years and I'm currently taking 11mg of methylprednisolone. Have had problems in the past getting below 10mg.
I unfortunately ran into a dental infection last week and was placed on Amoxicillin.
During this time I have found that my PMR symptoms have improved and I'm feeling significantly better.
Wondering if this is a coincidence or if there is a direct cause and affect relationship going on?
Has anyone else ever experienced this and does anyone know if there is anything in the literature that addresses this affect?
0 likes, 6 replies
Anhaga rocketman42
Posted
It's possible that the tooth infection was contributing to your overall inflammation load. Others have found that although clearing up a dental problem doesn't "cure" PMR it seems to make a lower dose easier to attain and they feel generally better.
constance.de rocketman42
Posted
I had a really bad attack of bronchitis whilst in hospital in March. They “dripped” antibiotics in night and day for 5 days. During that time I had far less PMR pain. But, as I was lying in bed most of the time (high fever) it’s perhaps not surprising.😏
margaret22251 rocketman42
Posted
i have had to go on Amoxicillian and something else for a kidney infection, but it has never improved pmr pain for me.
but someone more experienced than me will come along and tell you more.
EileenH rocketman42
Posted
A lot of people have commented that they feel better while on abx. The effect doesn't last though.
My husband has a colleague whose wife had what appeared to be PMR. She reacted badly to pred (I have no idea what dose, I suspect probably higher than was needed but I don't know). He persuaded her doctors in Hungary to try long term antibiotics which they had noted had a similar effect to yours - again, no idea what or what dose. It apparently worked to get her PMR into remission - or to cure whatever was causing it. I, on the other hand, have never had any relief from antibiotics at all.
As a mechanism - antibiotics do have an antiinflammatory effect. And as Anhaga says - maybe the dental infection was contributing to the way you felt.
rocketman42 EileenH
Posted
amkoffee rocketman42
Posted
I just finished a 2 week course of amoxicillin and although it did clear up my chest infection it didn't help my PMR. I guess you are one of the few lucky ones.