Any success with Tamulosin or Vesomni?

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I have an enlarged prostate which is causing me to pee a few times a night, caused by weak stream and bladder retention and my bladder telling me I need to pee, even when there seems to be almost nothing to pee. My doctor first prescribed tamulosin tablets a couple of months ago, but after a month there seemed to be no difference- still multiple unsatisfactory trips to the bathroom every night, with the knock-on effect of losing a lot of sleep. Now he's put me on Vesomni, which after 3 weeks also doesn't seem to be having much effect. Should I persist with the medication? Has anyone found that it takes longer to take effect, but does help in the end? Very grateful for any advice.

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    How bad is your bladder retention? If it is bad enough, you may want to try self cathing just before bed to empty your bladder. You should have longer sleep this way. Hank

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      My urologist always said "cathing is freedom" which I didn't understand until I needed to go to the hospital ER with 1.4L of urine in my bladder that couldn't come out. If only I had some catheters on hand for situations like this. Once I did learn cathing, which I did for 4 months (5x a day) between surgeries, it felt like I had more control over my situation.

      I had a great nurse at the doctor's office teach me how to properly cath to avoid infection, etc. You get used to it after a few times...

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    For several years I was using Tamsulosin while catheterizing. It allowed me to wait a little longer until I had to use the catheter again, which was helpful when outside my home. The effect wore off over several years though and the Tamsulosin was not helping much. It also caused RE (Retrograde Ejaculation) within the first 12 hours after taking it. In the second 12 hours I did not have RE but had lackluster orgasm from the drugged prostate. I stopped using the Tamsulosin (because I am using catheters to urinate) and the sexual performance came back. This is probably why a lot of guys claim better sexual performance after a prostate procedure. they stopped taking Tamsulosin.

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