Anyone else struggle to hold suppositories ?

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Im currently on my second day taking (Pentasa 1g) Suppository.

I got told to take it before bed, but thats when my bowel is more active.

If i pop it in before bed, i normally go to the toilet 1 hour after inserting it.

I got told taking it before bed is the best time, But i find mornings i dont go to the toilet for around 4-5 hours. 

Any advice on how long it takes to dissolve? Is it fine to go to the toilet (1 hour) after inserting the suppository ?



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  • Posted

    Before bed is best, you need to get to sleep so you don't have to expel it

    I would ask for MesalaMine liquid enemas instead, suppositories don't get even near the area of the intestine that has trauma

    The mesalaMine has many interactions with other drugs, you should check the list and perhaps avoid taking drugs that are listed under the major category

    If you see results after using the enemas, then don't stop using them just because your symptoms are gone, you've wounded the UC but you haven't killed the snake!

    Also eat 2-3 coconut milk yogurts per day

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  • Posted

    Also, if you eat red meat, you.might consider stopping to see if that also helps heal you more AFTER using my other suggestions
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  • Posted

    I take pentesa oral tablets because i cant retain suppositries. Ifbyour having a flare up i use predfoam. It is great and stays up.
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  • Posted

    Hello Thomas, 

    I think the reason they tell you to use it before bed is because it stays in longer (overnight) so if you think it will stay in longer if you use it in the morning then give it a go. Just double-check with your doctor first though. 

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