Anyone taking 15mg Mirtazapine with 10mg Escitilopram?

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I was initially prescribed 30mg Mirtazapine about 7 weeks ago, was fine for a while, then I had a major family upset which triggered my anxiety, so GP up'd dose to 45mg, this was too much for me and my anxiety worse.

My mental health nurse specialist, got me tapering off 30mg to 15mg Mirtazapine ( 30mg for 3 days then 15mg for 4 days introducing 10mg Escitilopram when down to 15mgs )

I stopped the Mirtazapine 2 days ago and feel horrendous, major panic attacks, shaking, hyperventilating, nausea etc.,

Can anyone give me any advice please, I haven't slept for more than 3-4 hours in 36 hours!!!

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  • Posted

    Hi Karen . Haven't tapered off this drug but years ago tapered off different one. Had all symptoms your having thought I would go mad. Tapering is a good idea though even though it seems bad now, after about day 10 I started feeling sane again, started getting about 5/6 hrs sleep instead of 2, the shaking , sweating , manic thoughts etc calmed down. Visit doc if you don't feel better soon , should feel better soon , probably still feel weak and strange for a while but takes a while to get out of system and back to normal, then I would really push your doctor to get to the route of anxiety??

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    • Posted

      Thank you Edwina,

      I'm considering taking 15mg Mirtazapine tonight and halving my Escitalopram in the morning?

      I can't cope like this anymore 😢

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    • Posted

      Hi , hang in there you can cope, if I and many others can you can. I've done cold turkey and tapered, it will get better, you'll look back soon and be glad you pushed through this. Really feel for you and aga who's in similar situation, as I totally know how you're feeling right now. Take it a day at a time even an hour at a time , keep talking, keep busy take comfort in the fact people are here for you . I know you feel rotten now but think tomorrow you may feel a little better and next day even better still. Get more reasurance from your doc that meds will work as it is making your anxiety worse, hang in there??

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    • Posted

      Thank you again Edwina.

      I'm concerned I might be intolerant to SSRIS as I had a bad reaction to Sertraline a few years ago too.

      I just feel so awful with the continuous panic attacks and nausea etc., and I'm so worn out 😢

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  • Posted

    Hi Karen , Im sorry to hear that you going thru this. I was in similar situation 16 days ago where my doctor stopped mirtazapine 15mg cold turkey after 3 months of taking it and put me on fluoxetine (ssri as escitilopram) what you are expieriencing are both withdrawl from mirtazapine and side effects of new antidepressant . I was there . Hell im still here but its gonna get better. Just hang on there. Antisickness tablets help. Your mirtazapine was stopped to quickly in effect you are getting your anxiety worse. Sending huuugs 😚😚

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    • Posted

      Thank you aga02916

      I'm considering taking 15mg Mirtazapine tonight and maybe halving the Escitilopram in the morning.

      I can't go through another night like the last two, I'm at my wits end even ended up at A&E last night as having major panic attacks all day and night!

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    • Posted

      Awww Karen that sounds horrible. How are you now ? Did you have this kind of bad panic attacks before starting escitilopram ? Or is it something new? I only had one major panic attack in my life , at work , they had to ring an ambulance as I was going on and on and on , couldnt breath , pin and needless in legs and hands, tight chest, heart palpitations and passing out. It was horrible and to have it day and night bless you 💖💖💖hope you were given something to calm you down and have something in case or to prevent panic attacks? If you dont you should go to doctors and demand something. Nobody should suffer like this 😚sending hugs xxxxxx im here for you 💖

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    • Posted

      Thank you aga02916

      I haven't had any panic attacks like this for over 25 years.

      Yes, the full hyperventilating, pins and needles, racing heart shaking! So frightening! They gave me a stronger Diazepam and gave me 4 more to bring home.

      Too scared to go to bed as I know I won't sleep and will start the whole cycle and it feels worse at night.

      Am going to ring my GP on Monday if no better 😢

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    • Posted

      I think you should or if you cant wait until monday , go to walk in centre and they have to take you. Bless you. Take one diazepam and try to get some sleep, try to switch off , try to think of something you enjoy , put negative thoughts on the side, I know its easier said than done but thinking about getting panic attack will get you in a state again . Its a vicious cirkle . You will get thru this , im here for you 💖💖

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    • Posted

      Thank you aga.

      Yes, if tonight's as bad I'm going to ring the local NHS Access centre.

      Here for you too 💖

      Are you switching to 2 new medications?

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    • Posted

      I hope you dont need to and you will have settled night but its good to have some way out.☺im only switching to fluoxetine 20mg, been 7 days on 10mg and now 8 days on 20mg. Sending hugs xxxxxx let me know how you feel xxx
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    • Posted

      Great you and Karen are supporting each other, it's lovely to see, feeling so crappy yet reasuring and helping each other, hope very shortly you can both congratulate each other on making progress, ??

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    • Posted

      Karen, take a diazapam before bed. You should sleep , doc gave you them for a reason. You won't get addicted if he only gave you four. They will help. It's just long term use isn't advised. They are often prescribed when coming off meds to calm or help sleep??

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    • Posted

      Hi Edwina , we are here to support all of us 😘😘😘 we will get thru this together , with ups and downs , but we will be able to share it and support each other 💖

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    • Posted

      Hi aga,

      Well got a few hours of sleep on and off, didn't go to bed stayed on the sofa!

      Still feeling nauseous and trembling very shaky and panicky.

      Did manage to force some toast down about 2am and again this morning.

      Just praying for an end to it all !

      How are you feeling today?

      💖

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    • Posted

      Aww bless you , sending hugs xxx feeling sick woke me up at 6am , had awful night , felt like I was on a boat. Had a nap on sofa from 8 till 11, about to have some soup. Hopefully this is going to help. Feeling anxious today and just weak and dizzy. And this horrible nasuea. But its better than few days ago so there is hope. Have you been to doctors ? Xxx
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    • Posted

      Oh no 🤦??? it's awful isn't it?!

      No haven't been yet, going to ring first thing in the morning unless I need to go to access centre before!

      Was meant to be having a mammogram tomorrow morning at 9.25am think I'm going to have to rearrange that now too. That always adds to my anxiety anyway as I was diagnosed with breast cancer 13 years ago, even though I'm now on the normal 3 yearly screening everyone in the UK is when they are over 50, still causes me more anxiety, it's a shame as I just wanted to get it done, but there is no way I can face that at the moment.

      Glad you got a few more hours sleep and hope you can manage to eat something sending hugs 🤗

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    • Posted

      Hi Karen , soo sorry you been thru this as well, I bet scan brings all the memories and thats makes you feel even more anxious. Im so glad you okay with it now. If you dont feel up to just change appointment , nothing is gonna happen and you dont need more anxiety on top of everything. I hope your GP is supportive and its gonna get sorted. You gotta let me know how it went 😚 I managed whole bowl of chicken soup and bite of cooked chicken. My tummy settled a little bit but I can hear it rumbling like a washing machine. Got hot and cold sweats straight away as well but im happy I had something. My stomach worries me cause im scared I might have ulcers as well. Got an appointment for gastroskopy and colonoskopy in 2 weeks. Im so scared ,I cant stop thinking about colonoskopy , I know its with sedation but some peoole say its painful and they cant even say it cause they under concious sedation. Had gastroskopy before I had gall bladder removed so this doesnt bother me as much. And Ive got MRI on wendesday for my back. Had to reschedule it before cause I got panic attack before and they dont give any sedatives and im claustrophobic. But needs to be done...........now just laying on sofa after food....

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    • Posted

      Glad you managed to eat something, oh I know what you mean about the stomach noises!

      Gosh sounds like you've got a lot on too with all of those procedures, like you say it adds to the anxiety too, I nearly had to have a colonoscopy a few years ago but they decided against it in the end. I've heard they're not very pleasant at all, do you have to drink that stuff before too?

      Hope your afternoon is a little easier 💖

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    • Posted

      Everything triggers my anxiety now , like im over sensitive or something like that. I think that once im in hospital I will chicken out and tell them not to do it. Yes they sent me some stuff to drink and tablets to take.....dont know why doc sent me for it , it wasnt my gp , it was hematologist Ive seen the other week , Ive got iron deficiency and been sent for iron infusions cause tablets make me sick. I had reverse reaction to infusion as well. Doctor wanted to level my iron with one infusion and I only managed to get half before I got reaction ggrrrrrr that didnt help me .....tbh im feeling better after food , not so sickly.But keep thinking about bed time and that I might feel bad again sad
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    • Posted

      I'm exactly the same, no particular trigger, just everything!!

      Gosh you are going through it with your other problems too 😢

      Glad your feeling a little better after eating, in the same, starting to dread night time and early morning as that's when I'm at my worst, and get major panic attacks!

      I could honestly throttle my GP for putting me through this, him and the mental health nurse specialist too 😡

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    • Posted

      I never used to be like this , I was strong bubbly 31 year old , happily married, with doggie , took antidepressants for ocd before but was year free and bam few months of stress and I got anxiety and now im scared of my own shadow . But it has to get better, I refuse to feel like this and im going to fight for my old self. Well Im trying now but it so hard when you feeling like poo 💩💩 im fed up with GPs , now I know that I cant even turn to them cause they not supportive .......

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    • Posted

      Would be lovely to be our old happy selves wouldn't it!

      I look at other people and wish I was like them and not like this pile of rubbish..... damn GPs 😡

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    • Posted

      Oh no aga😢

      I'm beginning to get the dread too!!

      Do you think it's the night/early hours thing? I'm bloody dreading it, might be another night on the sofa!!

      Did you feel better for a while after eating?

      I managed to eat something earlier but know the nausea, panic, shaking, etc is going to be back again........ how much longer can this go on 😢

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    • Posted

      Im just questioning everything, if I need medications, what if they going to make me worse, what if im going to feel like this forever, I start thinking about work that I have to go back to on friday and feeling like this its paralyzing. Just feeling fed up 😫anxiety is off the charts , never felt like this before , even before antidepressants. Im so scared 😫😫😫🤕

      I felt better after food buy only for a while , then I started feeling sick again with trembeling and now with nasuea and anxiety and thoughts. How are you feeling now Karen ? X

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    • Posted

      I felt a bit better after eating. But I know it's not going to last!

      Too scared to go to bed again, just don't know what to do, can't carry on like this!!!!

      Probably thinking about going back to work is making you feel more anxious too, I don't know about you, but I start panicking about things before they are here or happen!! I'm anxious about everything!!

      So scared of having more panic attacks too!!

      Try to hang in there, we've got to beat this......god knows how though!! 💖

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    • Posted

      I think the other problem is I now associate going to bed with having a panic attack!

      Just don't know what to do anymore 😢 Xx

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    • Posted

      Im sorry for winging Karen , im just so fed up atm. Thought I had good day but nooooo stupid thoughts keeps coming and then I blame meds for it. If I didnt have to go back to work for a while until I get better I wouldnt stress so much. But I dont get sick pay so cant really afford to stay off. Im exactly the same , instead of concetrating on present I keep thinking about future and things lol well thats what anxiety is lol hubby tells me to give time for meds to work but you know when you just feeling so fed and ill. Just think about going to doctors tomorrow and that something is gonna get done hopefully about how you feeling 😗😗

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    • Posted

      Yes I know , but what if you take diazepam 1hr before you go to bed ? Or just go to bed to sleep when you really tired.try to read a book or watch movie? I know easier said than done tho
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    • Posted

      Aga you are not whinging!! I feel exactly the same, so worn out and so scared 😳

      I worked in childcare for 24years, but had to give it up earlier this year, I broke my foot last June and was in a cast until August, then I lost my mum in September, I decided t couldn't face going back what with all of that and my anxiety, ironically a few months back I felt I could face it again, but there is no way!! Meant to be starting a business with another lady doing childminding but can't focus on getting any of that started either!!

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    • Posted

      And the worst of it is, we managed to get tickets to see Coldplay in Cardiff, bought them last October, two days before the concert on the 12th July, this all started, so I couldn't go as needed to be close to the loo...... I was devastated!!

      That's how much this bloody illness ruins your life.....plus stupid GPS 😡 Xx

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    • Posted

      Awww so sorry , you have been thru a lot , bless you 😗😗 I really hope you will be back to your old self , most important thing is to not give up and always have hope. And there is always way out. But with anxiety it seems like there is not and thats an issue. We just overthink everything and we cant cotrol it. Stupid irrational thoughts. When I take some diazepam I feel like my old self , cause physical symptoms of stress disapear , no banging heart , I can think clearly. I just hope I will be able to be like this only on fluoxetine as I dont want to depend on benzos xx

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    • Posted

      So many things ruined and not done cause of it and we only have one life and we locked inside our heads gggggrrrrrr and yes gps , dont get me started on this again. My hubby said that for my next visit he walks in with me , that is enough of docs not taking me seriously
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    • Posted

      Diazepam are the only thing that makes me feel half okish! My GP will only give me 2mg ones now though, well I can tell you they are not lasting five minutes at the moment, he used to give me 5mg ones too but wanted me to cut back..... no chance! Thankfully a&e gave me 4 5mg ones but I only have one left, but one I've my neighbours told my husband they have some if I need them.

      How do these GPs think we can get through this without extra medication?!

      I hope you have a better night, I'm dreading it, don't know whether to go to bed or not xx

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    • Posted

      Doctors dont have a clue. Especially mine. They dont want to give diazepam cause they addicted but yet throwing prescription for ADs. Its easier to come off benzos than ADs im telling you. Maybe have this 5mg tablet before bed to prevent panic attack. And just read book or talk to me 🤗im in bed now but cant sleep, waiting untill I feel really tired , thats when I fall asleep. Demand 5mg diazepam of doctor, short term just to help you cope with side effects of AD and maybe sleeping pills xxz

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    • Posted

      No they didn't have a clue, yet the dr at a&e had no hesitation in giving me one to take whilst I was there and the other 4 to bring home.

      My GP will get a copy of this, but I bet he still doesn't listen, they just seem to think ....oh it's ok you can ride it out.... but you can't!

      Just taken another Escitilopram, don't know if it's best to take them at night or in the morning, mental health nurse specialist said morning a&e dr said night!!! That's my 6th one, I feel tired but know exactly what's going to happen xx

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    • Posted

      I take mine on a night time , to avoid side effects during the day , dont think about anything bad happening, take diazepam so you wont get panic attack. I took some 3hrs ago , needed to x
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    • Posted

      Hi Aga, your anxiety is making you continuously worry about going back to work, like Karen worrying about bedtime and how it will be bad again, our anxiety actually convinces us it will be bad, it's terrible. Try to think tonight I may get a good sleep and start feeling better soon, both of you, also think you could feel better when you go back to work, give it a try if not make an excuse but you will have tried. You need o keep your strength up, try to eat something, know how you feel when you say you just want it to go, I was so impatient and worried constantly that I would never feel better, it will pass, know it seems never ending and hopeless, it isn't, glad you've got each other , I and many others went through this alone , was scared stiff, thought I would go round bend. Stick in there your both stronger than you think. Also get those doctors to listen, tell them what you've been through, they should be reasuring you and giving you all help and options available. Hope tomorrow's better??

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    • Posted

      Thank you Edwina 😗I know avoidance is the worst thing I can do. I am going back to work, I have to , not only for money but for myself , to go to people. But Ive been off for 3 weeks and im just stressed coming back, that I will feel s**t and stressed over there , its going to be a nightmare working with side effects. But I need to get thru this. Thank you for your words and support Edwina, really made me think and made me feel better 😘hope you are feeling okay xxx

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    • Posted

      Thank you Edwina, you are right about avoidance, logically I know it's my mind telling me it will happen! But sadly I can't think logically at the moment!

      It's reassuring to know that from yours and others experiences there will, hopefully be a light at the end of the tunnel.

      Thank you

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    • Posted

      Are you off to bed now ? Let me know how doctors visit went x thinking of you 😗😗😗😗

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