Anyone tried cutting Omeprazole tablet in half to lower the dose - preparing to try to taper off PPI

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So I’m going to soon try coming off my PPI.  I take Omeprazole 20mg tablets 1 tablet per day. Instead of trying to taper off by taking it every other day, I may first need to reduce the dose to 10mg every day for a bit.  I know the directions say not to cut or crush the tablets......but curious to know if anyone has tried cutting them to lessen the dose and if so, did it work?  I’ll add that I’m int U.S.  20mg tabs are the lowest dose available over the counter.  Thanks!

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  • Posted

    I tried a number of times. I'm currently taking 1 20mg tablet every 2-3 days and doing ok, ive had to massively change my diet and im currently taking 2 x 150mg ranitidine a day to help

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  • Posted

    I just cut them in half and they still worked but i would def get yourself some ranitidine to assist as the rebound can be a nightmare
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    • Posted

      Thanks. I’m definitely going to take ranitidine as I try to taper off the PPI. I’ve stopped drinking coffee and am trying to avoid other triggers as well.  Will start the slow taper off Omeprazole soon.  Have another doctor appointment first so I can have a good plan.  
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  • Posted

    It was hell the first few years with the stomach issues. I was first taking them a few years ago. I was told don't stay on too long because. it depletes minerals in our bones. I have had to change my diet and eat only organic. What is most helpful is lime water. I squeeze half a lime or whole lime in water when i am having reflux or stomach problems. Also, use a bit of baking soda with water when I need a bit more help.

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