Anyone tried cutting Omeprazole tablet in half to lower the dose - preparing to try to taper off PPI

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So I’m going to soon try coming off my PPI.  I take Omeprazole 20mg tablets 1 tablet per day. Instead of trying to taper off by taking it every other day, I may first need to reduce the dose to 10mg every day for a bit.  I know the directions say not to cut or crush the tablets......but curious to know if anyone has tried cutting them to lessen the dose and if so, did it work?  I’ll add that I’m int U.S.  20mg tabs are the lowest dose available over the counter.  Thanks!

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  • Posted

    Iv jus been diagnosed I am on omeprozole 20mg at moment. I'm going to try n lower mine too eventually. I haven't tried cutting em but will do. Thanks

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  • Posted

    I tried a number of times. I'm currently taking 1 20mg tablet every 2-3 days and doing ok, ive had to massively change my diet and im currently taking 2 x 150mg ranitidine a day to help

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    • Posted

      Hi Nellythe - did you try cutting the 20mg in half...as in with a knife or pill cutter? Trying to figure out if the pill still works if cut.  Also, what kind of diet changes did you make?
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  • Posted

    I just cut them in half and they still worked but i would def get yourself some ranitidine to assist as the rebound can be a nightmare
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    • Posted

      Thanks. I’m definitely going to take ranitidine as I try to taper off the PPI. I’ve stopped drinking coffee and am trying to avoid other triggers as well.  Will start the slow taper off Omeprazole soon.  Have another doctor appointment first so I can have a good plan.  
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