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Avodart Dutaseride.

Posted , 9 users are following.

graham90475
graham90475

hi all. Just a recap on my recent posts. Been to docs today. Explained the nightmare I was having on a year of Finesteride. Told him I had stopped a couple go days ago. Lack of libido, sensitivity, man boobs etc. I have noticed, as I have now retired, hence not as physically active, I feel this has not helped my condition or health in general. He has said to try Avodart to go with my Doxozasin. I will give them a try over the next couple of months to see if they suite me better. My last PSA was - 1.1 but I presume the finesteride impacts on the reading. I realise this is the same type of drug as Finesteride but will give it a try and if run into the same problem. I'll have a word with the doc. They don't seem very keen to prescribe cialis in the UK. Cost I presume. Any input opinions would be greatly appreciated. Any one on Avodart/ Dutasteride?

0 likes, 25 replies

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  • Howard31850
    Howard31850 graham90475

    Posted

    Yes - I have had experience with these drugs. I started with Proscar for 5 years and had the same side effects as you - totally devastated side effects. True it did reduce my PSA by half and my prostate size but that wore off after a few years and both went back to their original levels and continued to climb.

    So my urologist put me on Avodart (dutasteride) .  That drug made the side effects much worse and now 5 years later I cannot get off of it since when I try my prostate grows like crazy due to DHT production. So I am having the worse of all worlds. Currently I do self-cathing every day (CIC) and am ok with that but Proscar/Avodart ruined my life at age 69. My advice to you: destroy those drugs before they destroy you!!

    • oldbuzzard
      oldbuzzard Howard31850

      Posted

      Howard - have you been evaluated to see if a procedure might reduce the size of your prostate enough to get you off the drugs and the cath? Even if your prostate grows back relatively quickly, I would think that having something like Rezum done every few years would be better than the drugs with all of their side effects and being chained to self cathing.
    • Howard31850
      Howard31850 oldbuzzard

      Posted

      Hi - yes but at 240gm I only qualify for a simple prostatectomy (either open or robotic) or FLA by Dr. Karamanian in Houston. For now I don't mind doing CIC and hope that one of the new experimental procedures being developed where they just inject a new drug into the prostate to shrink it will get approval soon. Thanks. Howard

    • Howard31850
      Howard31850 hank1953

      Posted

      Hi Hank- yes I forgot to mention HoLep - that is an option for me too. I just worry about incontinence as it destroys the inner sphincter so it necessary to do Kiegel exercises to keep from dripping. Then there is the RE issue too. I don't mind CIC at all thanks to all my friends here who taught me how to do it 2 years ago. I am hoping one of these new injection procedures will get accelerated approval and then I would just need a simple once a year injection to restore my prostate. Probably my prostate itself is acting like a middle sphincter muscle at this time. Howard

    • hank1953
      hank1953 Howard31850

      Posted

      You are not the only one. I've been waiting for that injection as well. 😀 Hank

    • Howard31850
      Howard31850 graham90475

      Posted

      Hello graham and hank - I will send you both a PM tomorrow with the links to the company and the Phase III results. If I write it here I will get blocked for sure.
  • chris15677
    chris15677 graham90475

    Posted

    I wonder if Big Pharma is preventing the advance of this answer to our prayers: From: Yigal Gat, BSc, MSc, MD, PhD, Andrology and Interventional Radiology Unit, Maayanei HaYeshua Medical Center, Bnei Brak, Israel; and Braun Center for Sub Micron Research, Department of Condensed Matter Physics, Weizmann Institute of Science, Rehovot, Israel.

    Who says:

    Benign prostate hyperplasia develops due to an impairment of the testicular venous drainage system in the erect posture of the human. Based on our fluid-mechanics analysis of the venous drainage in the reproductive system, and the results of the developed treatment, the following statements can be made:

    1

    Benign prostate hypertrophy is caused by increased hydrostatic pressure in the prostate drainage system, while benign prostate hyperplasia is caused by an excessively high concentration of free testosterone; both arriving from the testes to the prostate by pathological back-pressure and back-flow through the testicular and the prostate drainage systems.

    2

    Eliminating the pathological hydrostatic pressure in the testicular venous drainage system by occlusion of the impaired ISVs, including all the associated venous bypasses and retroperitoneal collaterals by super-selective transvenous sclerotherapy or by microsurgery, eliminates the venous back-pressure and the back-flow of blood to the prostate. This reduces its exposure to elevated free testosterone. This initially reduces benign prostate hypertrophy, and subsequently, at least partially, reverses benign prostate hyperplasia.

    3

    We recommend that patients with BPH be examined for bilateral varicocele and be treated according to the suggested treatment.

    Read all about it here: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1439-0272.2008.00883.x

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