B12 Deficiency & Pernicious Anaemia

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After having blood tests last week I was diagnosed with a severe vitamin B12 deficiency and possible pernicious anaemia and have been started immediately on B12 injections (had 3 up to now with 2 more this week).

My b12 level was showing at just 150 and I was told this should be 190 and that this is the cause for me being so lethargic, having no energy and feeling so run down for so long.

I am now wondering when I should start feeling an effect of the vitamin b12 levels. One nurse told me it would be having an effect after the third, another said I wont feel any benefit until a few weeks after the 5th one and that I must then have them every three months to keep me topped up.

Im currently waiting to hear bk from a blood doctor at the local hospital as my GP is unsure whether I am suffering from pernicious anaemia or not due to my age (I am 24) so Im feeling rather confused at the moment. My full blood count was fine and my iron levels showed up fine too. Any help would be gratefully received.

Thanks in advance.

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5 Replies

  • Posted

    i am in the exact boat as you!!!! I have had all five injections now and i actually feel worse. my doctors is not being helpful at all and i am still waiting on results to come back. I am having a lot of symptoms and feel like i am going mad!!! x
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  • Posted


    It can take months more than weeks to feel better with B12 treatment. Its taken years to get depleted and can take time before the body stores are replenished and all faulty bloodcells have been replaced by good healthy ones, my explanation any way! In my case I initially went back to GP saying are you sure you got this right, but after some 3 months I did feel a lot better and started to depend on the B12 jab to keep me feeling good. So hang on in there, be patient!

    Kind regards,


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  • Posted

    I was diagnosed with pernacious anemia in 1998 and have since been taking B12 injections. If I remember correctly it took me close to 1 year to start feeling whole again. For 2 years now I get the shots once every 2 weeks and it takes about 30 minutes before I feel better. So, don't dispair you will soon reach a level where you will almost feel better instantly. Your dosage may need adjustment.
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  • Posted

    :lol: i am on 3 a day ferrous sulphate 200mg Iron tabs but they have made me gain weight and i fart alot and my stools have turned black like dark green i have heavy menstal periods and the doctor is still running tests on my blood i am tired all the time but have never been offered vitamin b12 by my gp but i have gone to the shop and got myself some and am now using it along sid my iron supliments and don't feel any better so i think my new blood test results will show that i am pernicions anaemia too and i am age 39 female and the doctor wants to give me a historectomy to stop my bleeding that he thinks is the cause and i am not ready for that i think i may want a child later on as i only got one at the moment and i dont know what to do but to just wait on my new blood test results but what i would like to know is this, will i ever make a full recovery? as my iron stores are 2.4 my GP says they are way to low for a female
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  • Posted

    I am wondering if you are feeling better after a year. I was diagnosed with low b-12 ...it was 110 and started weekly injections. I have had four and then I am on monthly injections. I am due for my first monthly injection next week. I have not had one for three weeks. I am taking daily b12 pills. I am actually feeling worse even though I am doing less. I have odd nerve signals and I am very tired. I feel like I am going crazy. Is there anyone out there who can help me as my doctors are vague about what is happening.
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