Best Treatment option for Graves?
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So the story is long to how I got here, but recently have been diagnosed w/ Graves after a thyroid storm out of no where. No prevoous thryoid issue, no family history. My doctor is treating me with/ Methimazole (started on high dose, have decreased sightly) and Propranolol. I get blood work weekly, but don't see him again for three months. I have read about Methimazole affecting liver, and my last blood work showed my levels were high. I went to a differnt doctor for a second opinion, his thoughts were much different: to STOP Propranolol and Methimazole IMMEDIATELY. He feels that methimazole is really bad for the liver even for temporary time frame. So, he prescribed Atenolol (50mg 2 tabs twice a day) as a replacement for propranolol. Im not entirely sure if he wants to stop the Methimazole simply bc of the liver, or in order to prepare for radioactive iodine therapy? Which I had explained to him, I needed to learn more about before proceeding. It's so confusing and frustrating because each doctor is different and every website and article is different. 2nd doctor says that new research says both Methimazole and PTU are both not good to be on during pregnancy, so my best option if I'd like to get pregnant in the next year or so, would be to do the Iodine therapy. My gynocolgoist seemed to agree. They put me back on birthcontrol, which i was reluctant, but they say its best until all is worked out. Other research seems to show that risk of liver damange is rare w/ methimazole and that some people are able to take oral meds temporarily and then go into remission, with out radioactive iodine. Lastly, I have obviously read many risks associated w/ the radio active therapy....immediate effects of being isolated for up to a week, longer term effects such as dry mouth, upset stomach, persistent fatigue, lung problems, infertility, etc, not to mention the need to take a synthetic thyorid med? Ahhh any help?? experiences w/ one treatment vs the other (specifically w/ Graves) and pros and cons??
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linda187 heathercc
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heathercc linda187
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Thank you so much for the info. I have always resisted medication when I am able to, I don't take ANY medication otherwise, until this. So it's been difficult to say the least, but trying to follow docotors orders until I know better at least. My original tests (during thyroid storm) were:
Free Thyroxine Index: 12.6
T3 Uptake: 44
Thyroxine (T4): 28.7
Thyroxine (T4) Free, Direct, S T4,Free(Direct) : greater than 7.7
Creatinine Serum: Low
Calcium, Serum: High
Last week blood work only tested & showed:
Thyroxine (T4) Free, Direct, S T4,Free(Direct) : 2.88 (reference 0.82 - 1.77) so getting closer to the normal range.
However:Alt (Sgpt): 87 Ref range 0-32 IU/L
Ast (Sgot): 69 Ref range 0-40 IU/L
Creatinine levels still low
I started on 60mg daily of methamizole for two weeks. Now they said to go down to 30 mg daily, but i am taking 20mg daily.
I do not see that they have tested any of the things you mentioned. However I do have a history of Vitamin D deficieny. The 2nd doctor has aslo prescribed VitD2 1.25mg 50,000 units gel caps- one a week. Will have to research the difference between Vit D2 vs D3.
I am vegetarian, boderline vegan but do eat small amout of dairy cheeses. Have started to cut some gluten. Otherwise mostly fruits, vegetables, grains, and nuts.
Awaiting my blood work done today. Interested to see where I am at. Really not sure what doctor will be on board with a less invasive treatment plan. I have not had much luck with that in the past when indicated that I don't want to take pills or high dosage if not needed. Have reached out to contact two hollistic doctors in the area to see if they treat Graves.
Again, appreciate the info. Thank you.
linda187 heathercc
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heathercc
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So just wanted to update, that I was scheduled for RAI. Was super nervous and was told no other options really. That since the methimazole was causing high liver levels that medication wasn't an option. I was off the medicine for 5 days- to "prep" for RAI, and saturday before the scheduled treatment, I had blood work, I kinda of panicked and "postponed" the treatment, like why the rush?? I got my blood work back and my thyroid levels were in normal range, liver levels had come down slightly. So i was put back on methimazole- this time only 5mg daily ( I was on 60mg a day prior during hyper/thyroid storm- like no wonder the liver levels were high) I kept asking if I lower dose, is there a chance liver will be ok and thyroid levels ok- everyone said no? but logically made sense to me? So now after 5more days back on medicine- thyroid levels still good, and liver levels almost back to normal! SO happy i decided to wait on the RAI. Praying I can control it this way and stay in normal range. Have to keep a close eye on it w blood work, but otherwise feeling soo much better and relieved that i dont need the RAI, at least not yet.
Does anyone have any info or thoughts on Iodine? Have read alot about it , and different diets and how they may affect hyper and hypo thyroidism.
linda187 heathercc
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