1. Community
  2. Bones, joints and muscles
  3. Rheumatoid Arthritis

Biologics/ MTX and side effects

Posted , 7 users are following.

dancingG
dancingG

 How long has anyone been on MTX or biologics without side effects?

0 likes, 10 replies

10 Replies

  • mrsmop
    mrsmop dancingG

    Posted

    I gave up taking MTX after 20 months.  I took it for an autoimmune skin condition.  It worked well on the disease.

    I now take MMF [Mycophenolate Mofetil] for my condition.  The side effects are fewer but it isn't quite as effective now.  I have been taking it for about 18 months.  I had been on 3g/day but had to reduce it to 2g per day.

    I haven't been on Biologics yet.

  • elspeth97587
    elspeth97587 dancingG

    Posted

    I started on Methotrexate tabs around 2005 but was feeling nauseated for about 4 days a week. When I moved to Reading my Rheumatologist changed me to sub-cut Methotrexate and I haven't had a problem since. I hope you get an answer and feel better soon.

  • Rowbirdie
    Rowbirdie dancingG

    Posted

    I ve had rituximab infusions ( every 6 months) for 1 and half years now with no side effects. I ve been on high dose of mxt for 2 and half years with minor side effects eg hair loss and brain fog on the day I take it. In general I am less robust emotionally but can't work out if it's the RA or meds- or just adapting to a major change in health! 

  • patyrod
    patyrod dancingG

    Posted

    I have been on methotrexate for a few months now.  I have hair loss, but that started before.  I suspect that it is caused by Plaquenil, which I have been taking for about nine months.  Since I have been taking methotrexate (10 mg a week), the only side effect I have noticed is lack of motivation.  I don't feel especially tired.  I just have a hard time getting myself to do anything, especially housework and paperwork. sad

    • Gloria814
      Gloria814 patyrod

      Posted

        I feel that same way too.   I used to like to read and now I don't have an interest in starting book or reading magazine.   And preparing dinner has become a big chore.   I do feel very fatigued esp by 4 or 5pm.   I sleep well til maybe 3AM and then awake til time to get up.    I am only on MTx 7.5mg---got too sick on 10mg.  But starting Humira in Dec

          Did start a med for depression--hoping it helps with anxiety and sleep

    • patyrod
      patyrod Gloria814

      Posted

      Let us know how it goes with the antidepressant.
  • ihavenonickname
    ihavenonickname dancingG

    Posted

    Enbrel 9 years before it became ineffective.

    Humira 1 year without inprovement

    Methotrexate immediate adverse reaction

    Rituximab in year 6 and doing great

    • ihavenonickname
      ihavenonickname dancingG

      Posted

      Yes...BUT

      I developed juvenile rheumatoid arthritis at age 11...back in 1962 during the dark ages of medicine...65 now.

      Began Enbrel 1999...so my JRA burned for decades. Enbrel was the first DMARD back in 1996 if my memory serves me well.

      You can use PM...I will answer all questions

      kind regards

      judith

Back to top

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.