Block and Replacement Therapy Carbimazole and Thyroxine
Posted , 3 users are following.
Hi I wasn't sure which forum to post on as Carbimazole was prescribed to me for Hyperthyrodism which I think was brought on by underlying Graves disease. Had hypothyroidism for 11ish years, then thyorid went haywire last year due to stress.
Now I am on block and replacement therapy. 30mg Carbimazole and 100mg Thyroxine daily. Has anyone used this method before and was it successful ?
I am trying to get my head round the benefits of this treatment, found this on the British Thyroid Foundation as they seem contradictory.
Block and replace: You continue taking CMZ, usually 20-40mg daily, or PTU, usually 200-400mg daily, to stop your thyroid gland producing thyroid hormone; and start taking levothyroxine (usually 100-150mcg daily) to replace the thyroid hormone your body would normally produce
My latest blood tests results: TSH 0.001 FT3 5.1 FT4 14.4 and I feel fine.
Any advice would be greatly appreciated. Thanks
1 like, 4 replies
joannagof jan64074
Posted
i have read a lot of thyroid articles and some say this is also really effective.
jan64074 joannagof
Posted
I should have been off block and replacement in June, but my endo has asked me to stay on it until November, so watch this space. Then once off block and replacement medication they will see how my thyroid behaves and then treat it. I've a feeling I will go back to being underactive again, which isn't a problem for me as I was underactive for 11 years and could cope with that.
What's really been depressing is the weight I've put on, which is nearly 1 and a half stone, since being on Carbimazole.
Will be glad to see the back of Graves and all my thyroid issues.
Hope you are ok, as maybe you have Graves and are trying B & R .
Have a great day
lou0000 jan64074
Posted
Which was easier to control - hypo or hyper? Weren on levothyroxine when you were hypo? I have graves but but may become hypo after thyroid surgery (which I must have for a lump). Thanks
jan64074 lou0000
Posted
Going hyper I noticed that I was feeling hotter with night sweats and my heart rate/blood pressure was up. But I was an egnima to my doctor as even though hyper I was putting on weight, thats when I was sent to see the Endo who found out I have graves.
So for me hypo was not a problem when they got the thyroxine dosage right, no symptoms and stable weight. In fact thats what I'm hoping is going to happen after I finish block and replacement. I did however get lots of symptoms when first diagnosed with hypo, then the symptoms settled down.
I have stressed my concerns to my Endo about coming off block and replacement and if within the first month I get hypo symptoms back, he wiill put me on 100 mg thyroxine as that was what I was on for 9 years without a problem. I told him I didn't want to go through the process of starting on 25mg, going to 50mg, then to 75mg, then to 100mg which was what I initially had to do and that's why it took so long to get dosage right as they start you off with small amounts and then gradually increase.
My thyroid when from hypo to hyper after a lot of stress, husband very ill and a house move.
God luck with your surgery and as said once thyroid under control with correct dosage of thyroxine you'll be fine.
I hope this helps![biggrin](https://patient.azureedge.net/forums/emoticons/biggrin.gif)