Bupropion for 9 months

Posted , 4 users are following.

Just thought I'd add as there was nothing about this drug listed save for one short post.

Took Burproprion for 9 months with Fluox for depression, I found

the step-up onto the drug fairly easy - only some medium level

anxiety and some agression/anger flashes, that said I am not especially

sensitive to those kind of side-effects, If you are might be worth using


What I would say is I mainly took this drug to try and resolve the total apathy I feel about just about everything and It did little to nothing

to relieve that nor did I feel any extra legwork vs depression (still Not wanting to leave the house, black mood, not thinking about the future etc). I can say I felt mentally sharper and perhaps slightly more social.

Also I recommend you research this drug carefully before taking it as

it has been implicated [u:9451624106]Directly[/u:9451624106] in deaths associated with cardiac issues etc. It also increases risk of siezure.

Coming off of the drug was a non issue - stopped dead no sideffects

beyond headache and feeling slightly blunted.

Anyways thought I'd write a little about it, It should be noted that the

drug is approved for use only for its Anti-smoking benefit in the UK

though it is used for depression elsewhere, if you want it for depression

in the UK you will need to get to a consultant I would think to get it off label.

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4 Replies

  • Posted

    I have been taking this for 5 weeks for depression (I'm not in the UK) - I am still also taking another AD (amitriptyline) but have reduced the dose of that and will reduce it further. I am now taking 300mg a day, my psychiatrist said I could go to 450mg a day if necessary. I am feeling more positive in general and less fatigued than when I was on 200mg of amitriptyline a day. Having had various meds trials over the last 18 months (fluoxetine, trazodone, venlafaxine, amitriptyline) and a month as an inpatient, finally something seems to be cutting through the lack of motivation and inability to look to the future, and a feeling of inevitability that everything will get worse till I can't take it any more and try to end it.

    I do really hope that I am finally on the right track. I wonder if anyone has any experience of it being used off-label in the UK?

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  • Posted

    Bupropion can be used as an antidepressant but it's not licensed for

    this indication in the UK.

    Our own drug information leaflet clearly says that it's a drug to aid smoking cessation.

    The Patient UK team

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  • Posted

    I was prescribed bupropion for anxiety in the beginning of December. My experience has been negative, as it doesn't appear to be a good fit for me. Initially, it seemed to help, but then increased/sustained anxiety followed. I started with 200 mg/day and still experienced anxiety, moved up to 300 mg/day and experienced a different type of anxiety, a sort of self-loathing mixed with a bleak perspective on everything. When I tried taking a 200 mg tablet, I experienced body pains. Today is my second day after moving back down to 200 mg/day. It's uncomfortable but not like 300 mg/day. I am temporarily taking Ambien for the insomnia that I believe the drug caused. The insomnia greatly worsened the anxiety. It seems that my experience has been pretty atypical, and I'm probably an outlier, but I really question the doctor's insistence on using this for my anxiety. I am seeing a different doctor on Friday and will discuss tapering off of the drug.

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    • Posted

      Been taking Bupropion 300mg a day for a number of years now & has helped me a lot so I'm a little afraid of stopping it. Anyone know of a ny long term side effects?

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