I was perfectly fit and well until end of last December when they put me on a small dosage of the Beta Blocker Bisoprolol due to ectopic heart beats that developed into Ventricular Tachycardia.
As soon as I started taking them, I described myself as being turned into an old man overnight who could no longer feel my lungs working, like a drunk zombie.
When they found me in a state of near collapse at work with a heart beat after oxygen given, of only 42bpm, they declared I was allergic to beta blockers and I have not taken any since March.
The symptoms however remain to this day and all the doctors, GPs, cardiologists, they refuse to even consider that beta blockers are to blame and so attribute my illness to anxiety from an abused childhood.
I do not feel anxious, I have worked for over 40 years with no symptoms of anxiety until the day they put me on beta blockers which seems to be a bit too much of a co-incidence.
Beta blockers however, they block adrenaline receptors in your Autonomic Nervous System, so I have symptoms of disruption to my ANS following taking medicine that not only disrupts your ANS, but that I reacted badly too. This seems rather more a logical reason for my current sickness, but how can I get anybody to even investigate the possibility?, they have all told each other it is anxiety so of course I cannot get past this presupposition.
I have found a detailed description of Autonomic Dysfunction on the Dantest site, they make medical machinery for the study of such. they list causes of Autonomic Neuropathy including medications that include " Drugs that decrease sympathetic activity (sympatholytics): alpha and beta blockers (i.e. metoprolol), barbiturates, anesthetics", but of course I would simply be told to not believe things I read on the web!
In addition, I possibly have a genetic predisposition to this as I have a Maternal cousin with Fibroid-Mialgia and Paternal half-sister with the same symptoms as POTs.
My current symptoms are ectopic beats and palpitations that occur mainly later in the day when I get tired, and after eating that can get so that every other heart beat is an ectopic.
My heart rate is around 30bpm faster than it used to be in any given situation, it also seems to fluctuate wildly doing the same activity.
Horrendous heartburn and the feeling that my esophagus is closed so that if I eat half what I used to, it feels painful, I feel full up with just a few mouthfuls.
My sense of hunger and thirst are diminished, a few weeks back I did a little experiment, I didn't eat a single thing for 42 hours and still didn't feel hungry.
Breathlessness and the feeling my lungs do not work automatically. When I talk to people now I sometimes forget to breath and they suddenly see me stop to take a gasp, when I fall asleep I keep waking with a gasp as I forget to breath.
My cardiologist did arrange a lung function test, but this only measured the capacity of my lungs, it didn't measure the lungs gaseous diffusion efficiency.
I had noticed when in hospital that the machine kept beeping because even awake, my blood oxygen level would fall to 87%
So I bought my own Oximeter, sometimes it can be as high as 98%, so there is obviously nothing mechanically wrong with my lungs, but generally it is in the low 90s when relaxing, when I go to sleep however, it spends half the night at 85%
I read that the ANS detects a low oxygen level in your blood and automatically adjusts your breathing.
An eighth month old cough. They tried me on a different beta blocker, Salotolol, this right away put me into a coughing frenzy so my GP told me to come off which I did, the bad cough went right away, but I have been left with a permanent dry cough that gets worst when I talk of when I have a shower it gets so I am nearly vomiting.
Exhaustion, utter exhaustion, I had to go to work to see O/H and chatted to a few friends, so I was there for about four hours, then I had a meal there, that must have used the last of my energy as I could muster up just enough energy to draw breath, had to sit down for a couple of hours before I could get up again. All my symptoms are worst when tired, so I have to spend the following day in bed after doing anything as strenuous as going out. I don't even have the mental energy to pass my time with computer games, often it is hard to force myself to do anything more than just sit and look at the floor.
Brain Fog, when I get exhausted my speech becomes slurred, I cannot walk straight and feel drunk, I have this all the time to a lesser extent.
Tingling in my feet, often when lying in my bed this expands to a quivering I feel throughout my whole body.
I now find myself waking in the night in order to urinate, as much as four times, full loads not a prostate trouble load.
I do not have the POTs symptom, I measured my heart rate as only going up by 20bpm when standing from lying down.