Can mirtazapine cause peripheral neuropathy
Posted , 23 users are following.
Hi. I'm in my late 40s and have been taking Mirtazaine for 3 years. In the last year I've had itches in my legs and burning feet. I came off the Mirt in mid November and have been exeriencing worse symptoms of peripheral neuropathy - itchy burning feet and pins and needles in my hands (mainly at night). I'm otherwise healthy (no diabetes) and wonder if the Mirt caused the neuropathy. Anyone else had similar?
1 like, 28 replies
daniel82425 gina18608
Edited
I have been taking 15mg of mirt for 2 weeks and it has worked for sleep but I now have numb feet . I had been on seroqel for sleep but it would make me anxious . Other than the numb feet I feel better on mirt. I also was prescibed cymbalta and 200mg of neurorotin for my new diagnosis of prostatitus. This is a frustrating choice between sleep or numbness off feet.
donna_2683541 gina18608
Edited
Hi I am taking Mirt which i believe it induces my restless legs...also when my skin is rubbed it leaves a tingle.Also my toes feel numb. I am sure this medication is to blame os this Peripheral??. Anyone else have this or am I taking rubbish. Im at my wits end. Diana
donna_2683541 gina18608
Posted
Hi Gina I think I have the same but I also have Restless Legs its driving me mad. I blame the Mitz for all this so i might try a different med. If it wasnt for Restless legs i could cope. x
paul08424 gina18608
Edited
OMG thats mad as ive got the same symptoms and problems and didnt think it may have been the mirts? im currently off them but suffering exactly the same problems. itchy skin burning feet but also losing strength in my hands arms and legs. Im also suffering terrible myoclonus and sleep jerks. i really hope this settles down as its wreaking havoc with my every day life. did you get to the bottom of it and if so did your problems resolve? Ive been referred to a neurologist but its my 4th time and each time they do nothing to help. Im really desperate now
jen35333 paul08424
Posted
hi paulo! hows your neuropathy now? im 4 mos off mirt and have burning skin sensation from my head to my toes! its maddening!
Samilynn9 jen35333
Posted
hello I was on for only 2 weeks, I took 12 pills 7.5 mg, two times 6mg And two times 3.75 mg. I stopped completely because I developed numb feet and other numb sensations in my body, burning down my arms, face, chest and back, small tremors in my hands and mouth and inside my body as well as some muscle twitches. I know I was only on for a short period of time but if anyone's still on here that experience these things and have now gotten better please post so that we can all feel that with time it will resolve?! I also have terrible insomnia...
s765 gina18608
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Hi gina18608 - just wondering if you have any further updates on your journey? I've been on Mirtazapine for many (10ish?) years now (varying dosage, currently 30mg) and over the last 4-5 yrs have started to experience some neurological problems including muscle twitching, cramping, numbness, cold feeling and neuro pains in my legs as well as a host of other odd symptoms.
Doctors currently seem stumped after several MRIs, neuro exams and countless blood tests. The only suggestion I've been given is that it's anxiety, but that's quite a leap given the number of symptoms. Worried this may permanent damage wrought by the drugs...
sarah43979 s765
Edited
hi do you have an update on this situation im currently waiting for a full body MRI scan as i have the same symptoms plus a massive and hard abdoman i have been of mirtazapine for 3weeks and still symptoms
Gareth666 s765
Posted
Ive been on 30mg for 3 years and i also have some strange pains and symptoms. My elbows don't straighten my arms are locked bent, no swelling or redness, but this ache and they click and its painful I've had many many blood tests and they couldn't figure it out but he then said it is a rare side effect of mirt and I'm having to come off them now when they saved my life i was deeply depressed and they worked wonders. Im hoping ill be okay on the lower dose (snapping a 15mg tablet) 7.5mg so i can avoid withdrawals.
Gareth666 gina18608
Posted
Ive also been on Mirt 30mg for 3 years and have been off work with joint pain for 4 months now.. in this time I've had a blood clot in my leg because i couldn't move as i have been. Torrid time but as I've dropped to 7.5mg over 5 weeks I've started feeling an improvement. Because the withdrawals are so severe I'm going to stay on 7.5mg and see if i get better. The withdrawals can last 9 + weeks so they say.
tess123 gina18608
Edited
my peripheral neuropathy started with mirtazipine. It caused metabolic disregulation, started with pain in my feet, burning and aching. i stopped the mirtazipine after 3 months ( i was always very slim but put on 2&1/2 stone in this time.) i lost the weight in the following 3 months. Unfortunately i didnt lose the neuropathy. 4 years later and im entering stage 3 neuropathy, its agony. its spread from legs and feet to hands and face. ive no quality of life , on disability, agony to walk but its even worse now the nerves are dying completely, cant feel my foot on the brake/accelerator so driving will stop soon. on gabapetin but its not helping much now. ive a wheelchair to look forward to eventually.
100% caused by mirtazipine