Can't lose weight (mirtazapine)

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Hi, I was diagnosed with bipolar back in July of this year. Incase treated for PND before hand from the January. Anyway I was on sertraline 150mg and Mirtazapine 30mg which saw me gain 20lbs, I've been off the Mirtazapine now for nearly 6months and I am struggling to even shift a pound. I've tried clean eating, low carb diets, weight watchers even restricting and nothing. It is really dragging me down and I feel like a hopeless fat mess.

I'm currently on lamotrigine 150mg and diazepam (only some days)

Anyway has any body had a similar experience where by they eventually lossed the mirtazapine weight?

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  • Posted

    Sorry to say I think the bad news is that sertraline and even lamotrigine which is supposed not to,  can also contribute to weight gain. The drugs mess with your appetite and your metabolism though it varies from person to person. It continues to be a problem for me, a fat blob. I think all you can do is keep eating healthily and the rest and hope your weight will  go down slowly.I'll be keepion an eye on the discussion in case someone has the answer.
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  • Posted

    I was on sertraline years ago and I actually found I lost a bit of weight.

    Now I'm on lamotrigine and valproate and have been for a few years now. Last summer I was really fit and busy and lost quite a bit of weight. I ended up having a decent figure which for me was remarkable. So you can lose weight on some of these drugs.

    But one thing to bear in mind is any underlying depression or anhedonia. Do you feel like exercising much? The only times I've managed to lose weight is when I've exercised heaps or had such bad depression I barely ate. So maybe doing heaps of exercise?

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    • Posted

      Hi, when I was on sertraline alone I too lost some weight, as soon as the mirtazapine was introduced it went down hill from there due to cravings. When it was stopped the cravings stopped enabling me to atleast attempt a diet or two. 6 month on and I'm completely at a loss, I do exercise every now and again but I had SPD at the end of my pregnancy and ended up on crutches, 14 month on I still have discomfort so it's a hit and miss. However I do think some exercise even if its walking abit more could atleast help with shifting some weight

      Thanks for your reply

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  • Posted

    I haven't experienced weight gains to medications where that is included in possible side effects, but I've also grappled with being overweight. For me, the process if one step forward, two back, three steps forward, one back, etc. I had to deal with addictions: caffeine being the most recent. I was shocked by how much more stable I've been without this upper, which I still have occasionally (I love good coffee!). Wine is on the list of what I had to deal with, after finding I had developed alcoholism, and now it is an occasional pleasure. And I had to deal with sugar addiction. Now I have very very few sugar foods. As ugly a truth as it is, I think the bipolar illness is made worse with those self-medicating items, not to mention the calories they contain. Last, I was advised to try gluten-free. Four years later and my weight is totally normal and depression a bit less, and almost no grass seed allergies. I hope any of this is helpful.
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