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Castrate resistant prostate cancer spread to bone

Posted , 3 users are following.

thomas06644
thomas06644

-Started Bicalutamide (casodex) and lucrin injection in June 2016

-Bone scan(Aug 2016): extensive bone metastasis 

- Metastatic castrate resistant since April 17 (based on PSA level)

- June 17: Bone scan showed further bone metastasis. CT scan is clear thus doctor doesn't suggest chemo yet

- what is the best drugs suitable for my case to slow down the bone metastasis? Thank you very much.

0 likes, 6 replies

6 Replies

  • richard98806
    richard98806 thomas06644

    Posted

    I can't give input at this time but I am interested in following discussion,  I had a RARP 3 months ago and everything went very well.  Biopsy indicated margins were clear, 30% of gland had cancer, gland was intact.  Gleason was a 4/3.  Pre tests also indicated no cancer anywhere else.  Well, first PSA is at .15.  Surgeon was quite suprised that anything but zero or negligable as a suprise.  At this stage it's a wait for 2 months and retest.  Obviously I am concerned and I know if this turns for the worse follow up treatments will be necessary.

    A good blog is available from National Cancer Institute (NCI) under "Ask Andrew", check it out

    • barney34567
      barney34567 richard98806

      Posted

      Join the club. I too had RARP and then the PSA climbed and is climbing. On your surgery pathology report was there mention of perineural invasion (PNI)? Was there lymphovascular invasion?

      Your urologist is doing what mine did. When I retested and the PSA rose I had a PSMA PET CT to determine the extent of the PCa.

      The fact that you had RARP as the first line of treatment is good, because all options are now available if needed.

  • richard98806
    richard98806 thomas06644

    Posted

    How long were you on the hormone therapy?
    • thomas06644
      thomas06644 richard98806

      Posted

      Since June 2016 I was on hormone therapy.

      PSA trend

      • June 16: 226

      • Nov 16: 13

      • Feb 17: 70

      • April 17: 542 (testosterone 1.4)

    • barney34567
      barney34567 thomas06644

      Posted

      Rather than look at more standard therapy options, have you or your medical  oncologist considered joining clinical trials?
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