Changed brand of Losartan

Posted , 15 users are following.

Hello everyone

I've been on Losartan Potassium 50mg for over a year now - always the same brand manufactured by TEVA UK and collected from Boots.  Today, my husband has picked up my prescription from a different branch of Boots which is manufactured by Laboratorios Liconsa in Spain and distributed by Sandoz Ltd (the name on the pack).

I know that the pharmacies have to supply the cheapest available at the time, but I thought it a bit strange that I have always had the same supplier for such a long time and suddenly it has changed now for the first time.  However, owing to my side effects from so many different pills, I'm a little concerned about switching manufacturer, and would be interested to hear what others think.

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  • Posted

    I'm so glad I found this discussion because, as I get older, I find that I think I may be imagining things and it's great to find others experiencing the same problems. I've just gone back to my local, small pharmacy to return the Sandoz Losartan that I collected yesterday in exchange for the Teva brand which, I assume, my body has now got used to. Each time the brand has changed my annoying cough has increased and, with the one brand, I now think that it wasn't a coincidence that the cramp in my legs was excruciating - worse and lasting longer than ever before. Doctors and other professionals may say that Losartan is Losartan whoever the manufacturer is but the experience of people taking it is a far more useful pointer when reactions are not quite what they're expected to be. Thanks to everyone who has commented.  

  • Posted

    Hi

    The main source of the idea that drugs produced by different companies can have significantly different effects are the drug companies themselves. It might be that the other contents might have an effect on absorption rates, which could effect the response to some drugs, but BP medications build up their effects over a number of weeks and loose their effects over a similar time span. Really if people experience an immediate change its unlikely to be the drug formulation. Drug production is a highly regulated activity and products are regularly subject to quality control tests, its usually in the supplement market that products are not as they should be. A company found to be producing a poor quality product would likely be out of business the next day, but drug companies in order to charge more for an exclusive product will even produce new drugs with no real differences to older products simply to charge more.

    It seems that people are more likely to worry about this in the USA, but drug companies are allowed to advertise directly to the public, often stressing quality issues. The NHS buys drugs under contract and keeps the cost down by doing so, generic drugs are often sourced from different suppliers.

    • Posted

      Laroxe,  the actual drug composition itself is likely to be much the same but the bindings/fillers and coatings used can be quite different.  Many people have drug allergies but I’m also sure some of us can be allergic to the add-ons as well.
  • Posted

    I agree about the other constituents of the pills being relevant, that's why I mentioned rates of absorption. However the very long lead in time, which is often over weeks would suggest this is very unlikely to cause problems. I also agree that people may be intolerant of some constituents, but this would usually be very obvious very quickly. These arguments don't mean that there are not some unexplained effects but perhaps help explain why Drs are not convinced about it. Having said that they tend to dismiss a lot of the effects of BP medication and in that they are very often wrong.

    • Posted

      I’m not a good example with my experience with medication - in fact, I’m probably  the medics’ worst nightmare, being highly allergic to loads of medications, confirmed by skin biopsy in some cases.   
  • Posted

    Just had my chemist change mine from teva after 2 years for these after 5 days I had double vision and ended up in a&e. For 5 hours. Took about 8 days to go. Went back and to doctors with blood pressure raising and lowering. Got my teva brand back but 3 weeks later got bells palsey. !!’ In the same eye first then my face. I blame the coating on these tablets. 

    • Posted

      Paula, what a nasty experience!  I’m feeling concerned about Teva themselves now after the recent recall of all their Valsartan pills.  Apparently, they have been tainted in production with a carcinogenic ingredient.  Talk about ‘our lives in their hands’!

      I hope you feel better again soon.

    • Posted

       Teva levothyroxine was withdrawn some time ago due to strength and manufacturing problems.

      Teva has just informed Thyroid UK that their levothyroxine is now back on the market (as from 17th October). We are extremely pleased to see that not only have they also introduced new dosages – 12.5mcg and 75mcg – but all their tablets are now lactose free. Thyroid UK is constantly being asked about lactose free levothyroxine and these are very expensive on the NHS. Teva levothyroxine tablets may well be the answer. 

      Teva tell us that they have changed the formulation of their tablets so do check the ingredients if you decide to move from your current brand. Although their clinical trials show that their tablet is stable in terms of patients being able to swap from one product to another, they also explain that prescribers of their levothyroxine tablets should continue to monitor their patients for any clinical signs and symptoms of adequate thyroid hormone replacement because some patients may require adjustments for reasons not related to the pharmaceutical properties of their tablet.

    • Posted

      I’d feel happier if our drugs were produced here in the  UK than in China!!
  • Posted

    My mom has been on losartan Potassium for years now, but recently has had trouble filling her script.  I have contacted TEVA and they have told me that they are discontinuing the product.  I dont know what to do. She has experienced horrible side effects on other brands of Losartan, does anyone know of an alternative to TEVA that is just as good? thank you
    • Posted

      I do hope the information you have received is incorrect - TEVA's Losartan is the only BP medication so far out of 8 different meds that my body is tolerating. 

      Certainly, there is nothing on the Web that mentions TEVA discontinuing Losartan.  Perhaps you can check with the Pharmacist?

  • Posted

    This is the reply i received yesterday from their customer service department.... 

    Thank you for contacting Teva Pharmaceuticals Customer Service Department. We wish we had better news, but Losartan Potassium Tablets have been obsoleted. We apologize for any inconveniences you have experienced with the availability of this product. Please contact your pharmacist or physician’s office for an alternative product. If you have additional questions, feel free to give us a call. Thank you for contacting Teva Customer Service.

     

    Customer Service

     

    Moderator comment: I have removed the email address as we do not publish these in the forums. If users wish to exchange contact details please use the Private Message service.

    • Posted

      Oh dear, that isn’t good news for your Mum and me or for anyone else who has problems with other medications.  My next prescription is due in a few weeks time......!
    • Posted

      Did your reply come from the UK offices ? It does not sound British in tone... obsoleted, physician office.

      Adnerb's answer may of course been by some one on the basis of present stock without knowing future production plans. 

    • Posted

      Derek’s hunch was spot on!  I have been in touch with TEVA UK - they have NO plans to discontinue Losartan Potassium in the UK for the foreseeable future.  Phewee!
    • Posted

      That is  the Losartan Potassium 50mg dose I am referring to.

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