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My 83 year old mothers methotrexate has just been increased to 20mg from 15mg as Consultant said we have not got the balance right yet as the pain comes back when we try to reduce prednisolone below 5mg daily. Looking at the last blood results just before hits most recent increase at yesterday's appointment, for the first time, one blood marker was out of the normal range. The MCV reads 32.1 when previously it has been 94.6. Been on methotrexate now since October 20 2015 so we are worried about what this MCV change might be showing. Obviously it didn't concern the Consultant which I guess is positive. Has this happened to anyone else or can anyone suggest what it might mean?
Thanks so much and hoping everyone is keeping well.
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