Chronic nausea for 15 years, still no answers!

I’ve been following this post for about a year: My 12-year-old daughter became ill almost two years ago, and we may have finally found a solution. She began suffering nausea daily after what we thought was a stomach bug. We took her to her primary care doctor and about a month into this, all labs (bloodwork and stool samples) came back unremarkable. Again, her primary symptom was nausea/decreased appetite, but she began to notice what we thought was some kind of reflux as well as something she referred to as “bubbles” (sensation in the gut and rising in her throat), occasional stomach pain, and occasional headaches. She became a very anxious person because she so often felt unwell and worried that she would vomit at school. She ended up getting two endoscopies, was diagnosed with gastritis, reflux, functional abdominal pain, etc. She was prescribed ondansetron, and told to take omeprazole for 3 mos (and then for a fourth mos when her symptoms continued). At the end of the 4th mos, her GI doc ordered allergy testing which was negative. The nausea and reflux persisted, and headaches and feeling unwell became more frequent. she was also taking antacids. I finally took her out of state to another GI doc who diagnosed her at our initial visit with abdominal migraines. I was somewhat familiar with abdominal migraines because of all the previous research I had done trying to figure out how to help her. The doc said she fits both cyclic vomiting syndrome and abdominal migraines - there’s a lot of overlap in the two, and you do NOT have to vomit to fit the criteria. He said some people just fight the vomiting part and contend primarily with nausea. Others have predominantly pain, as many of the articles about abdominal migraines will state. My daughter would also get pale and clammy now and then, have an occasional day or two every other month or so where she was utterly fatigued, chilled, and achey, and then be over it in 24 to 36 hours (except for the nausea, of course). I couldn’t figure it out. This new GI doc prescribed a low dose of amitriptyline (commonly used for depression at higher doses, but also for migraines at lower doses). He also highly recommended a good sleep routine. We’re coming up on two weeks since beginning the medication, and I’m more hopeful than I’ve ever been. It’s difficult - we’ve been down this road so many times only to be disappointed, but this is the longest period of time that she has done well. This is the most energized she’s been, her appetite is great, and I feel like I have my happy-go-lucky child back. I’m praying that this persists, and optimistic enough that I wanted to share with others on this board. I sincerely hope this helps you or someone else out there. It’s been a long road for us, and I know you and many others have struggled far longer. All the best to you.

Please share what was used in your IV medication that stopped your nausea, My son is experiencing this for 5 years off and on.

Since your stomach lining was inflamed, was gastritis ever mentioned? Maybe ask for a stool test since this hasn't been done.

I haven't read everyone's replies but has low stomach acid been mentioned. I know I have been having all these things and been told I have "silent reflux" no acid feeling but the acid going on makes you feel nauseated, dizzy, headache. Have you tried any digestive enzymes?

did you find out what caused it? Ive been suffering for months with nausea, i can have one really good day but then i could suffer with it again for the next few days. I haven't been able to go out anywhere because i feel sick. I do have a fear of feeling sick so this is obviously making me feel worried everyday. I have been to the doctors and had blood tests done but all came back negative. Anyone able to help??

I'm 36 years old, identify as female, and was born female. I've had trouble with chronic nausea for years. Had a colonoscopy and endoscopy, been tested for allergies and parasites, had imaging done. Everything always comes back normal. I've tried gluten-free, dairy-free, low FODMAP, and plant-based diets, as well as a variety of meds. Nothing seems to change. I have depression, although I manage it fairly well most of the time with the help of counseling, medication, and self-care. I don't really struggle with anxiety, however. In fact, my work is in an unpredictable and high-stress field and I really enjoy it. I can't really remember when this problem with chronic nausea started, so it must have been gradual? But now it's everyday and has been for years. Anyway, it's exhausting and frustrating and depressing and has negatively impacted my career and relationships over the years.

I wish I had something helpful to add. Just sharing my experience. I hope you find relief soon.

Can we be friends? i seriously feel like i could have written this. i found your post when I was on yet another Google search trying to find out what the heck could be wrong with ME. Eugh! So familiar. i am a 37 year old mom of one, and have been struggling with chronic nausea/indigestion for about a year and a half now. At first it lasted about 6 weeks and went away for a few months, but its been back for a good 6 months now. My anxiety and depression is at an all time high. I am struggling. I have lost weight. I would not wish this on my worst enemy. I have had tons if blood tests, the h pylori breath test, two abdominal ultrasounds, and am currently trying "all the medications" while I wait for the dreaded scope, which js 6 more weeks away. Zantac, Pepcid, Tagamet, Prilosec, Nexium, and now Prevacid. I feel like they make me worse? The nausea starts during or shortly after eating usually, and it feels like a "pressure" or a need to burp. I have not gone to a restaurant in over a year, and cant bring myself to eat with people anymore. 😦