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Cn3 smear test, normal biopsy ? Confused!!

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sarah08934
sarah08934

I had a smear test that came back as high grade abnormal cells, i had a colospy and the doctor was going to do lazer treatment but couldnt reach my cervix, so i was ment to have it done under G.A. and also took a biopsy, the results from the biopsy have came back that i have no abnormal cells of the cervix. They are going to have a meeting and let me know what they are going to do. Has anyone else had this? Im really confused!!

0 likes, 3 replies

3 Replies

  • Purpledobermann
    Purpledobermann sarah08934

    Posted

    Sorry, just to be clear I am reading this correctly: You were meant to have it done under G.A. or you actually had it done under G.A? There arer several questions raised by the way this was all addressed.

    Firstly, It is not all that unusual to get false positive results during smear. Some doctors repeat smear to confirm, but most go ahead for colposcopy and punch biopsy.

     However, I am confused: If they could not reach the cervix, how did they perform the  biopsy during colposcopy? Or is it that you actually had biopsy taken under G.A.? 

    And if so, did they actually perform laser ablation straight and sent that tissue for a biopsy? This is very important. During laser ablation it is possible to actually destroy the tissue making biopsy inconclusive. It could well be that any abnormal cells that may have existed were grouped on the edge of the specimen removed and got destroyed in the procedure making the sample....unreadable and quite useless diagnostically.

    During the original pap test they should have first excluded the possibility of any infection that could have given false-positive results (it is what they are meant to do in parallel to smear test anyway but some don't always bother... I would ask them about this - perhaps they did and perhaps not).

    CIN3 PAP , if correct, would most definitely be supported by a punch biopsy which is more reliable than the pap test and should probably better be done BEFORE lasering or cutting away.... therefore, either the pap was off for reasons described above, OR lasering messed up the sample in - ideally punch biopsy should have been done to assess the changes are correct and then opt for EITHER laser ablation or conization. Alternatively if it made more sense to go aggressively they should have considered conization instead of LEEP to preserve the edges and not compromise the sample. The latter gives a clean unburned edge and makes for better biopsy specimen.

    If you can, please do let me know how they decide to proceed as I am very curious.

    With regards to your health moving forward, all they can do is repeat smear within 3 months or so (not sure about the waiting period after LEEP). OR they can perform colposcopy, hopefully they can reach cervix and actually perform a punch biopsy next time.

    For next PAP I would ask them to take 2-3 samples if possible. And test for infections while they are at it this time - if they did not do so last time.

    Source: gyn. oncology specialist that treated me for my CIN3...

     

    • sarah08934
      sarah08934 Purpledobermann

      Posted

      Hi thanks for your reply, i didnt have any treatment, at the colposcopy clinic he said he couldnt do the lazer treatment as he might hit my vaginal walls so i have to be booked in to have it done under G.A. in a few weeks time,he took 4 punch biopsies and said he had biopsied a high grade lesion. I recived the letter saying theres no abnormality of the cells of my cervix and said they are very suprised by this and they will have a meeting then be in touch with me. Im just really confused by it all.
    • Purpledobermann
      Purpledobermann sarah08934

      Posted

      Ah ok. That's a bit better.

      I am confused too...because you said he could not reach your cervix to perform a colposcopy so how the heck did he manage to do punch biopsy right on the suspect lesion smile  must be a highly intuitive doc smile

      Anyway, either something is wrong with the sample he took or with pap test.

      For your peace of mind it would probably be a good idea to repeat pap and colposcopy and decide based on second set of results before deciding to put you under. But, at the same time If it is CIN2 or 3 indeed however, they will have to put you under anyway for LEEP or conization. Both are acceptable ways to proceed as pertaining to your health so see what makes most sense to you and to them. Either way it has to either be reasessed. Good that they are convening. Is this private or public healthcare?

      Wishing you the best outcome in any case. 

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