Coming off 37.5 immediate release tablets

Posted , 3 users are following.

Hi all,

I'm down to what i think is half of a 37.5 tablet. 1/4 in the morning and then 1/4 in the eve. The maximum ive been on is 2 x 37.5 a day.

Have any of you managed a successful wean from these tablets? obviuosly with beads it would be easier to see how much im reducing.

any advice?

0 likes, 7 replies

7 Replies

  • Posted

    Hi Nixy

    That is my situation exactly! 37.5 twice a day. I am just biting them in half with a view to have just 18mg a day but I am just having the half every morning. Its unbelievable to think such a small amount still has. I am going to every other day for a week starting Monday and then see how that goes. Some has mentioned CBD oil but i'm not sure?

    • Posted

      Hi Maz,

      I'm reluctant to try the CBD oil

      at the moment - just want to be free of all chemicals.

      For me, its only day two of taking two

      crumbs a day ( sorry trying to keep

      my sense of humour). Apparantly at day 4 you feel the withdrawal.. lets keep eachother posted x

    • Posted

      Hi Nixy, sorry I've not been on for a while ok so here is my update. I started to take 2,000 omega 3 a day and did start on 720mg CBD capsules. my honest comment is I have no idea if they are helping or not, I certainly don't feel any obvious benefit so may stop the CBD. I have had "vertigo" since stopping over 2 weeks ago now whooshing brain, shakes but I think my biggest withdrawal symptom is by far my mood and emotional state. I often get "weepy" for little or no reason and I am irritable and have a very short fuse. I feel like a completely different person. don't get me wrong I am functioning, working in a high pressured position full time and for people who dont know me well they probably have no idea there has been a change. however I know I have withdrawn from those close to me I have developed a somewhat "woe is me, victim" attitude which is just sooo not me. I feel incredibly lonely and no-one is there for me and I have to sort myself out as none else is really there for you. even as I write this I know I sound pathetic!!!! I am usually so proactive and very much the "head of the family" I fear this has changed dramatically and I worry I have changed for good and I don't like this me! But how would I know I've been on anti d 's. for 20 years so it's all guess work. look it's been 3 weeks only so I am clinging onto the belief that it will improve the trouble is nobody knows (the doctors certainly don't) I visited mine last week and just broke down crying the whole appointed, which again is not me, whilst she was sympathetic she offered no answers! Sorry to make this so lengthy just giving you an update of where I am now. Hope you are getting on ok, I'll keep you posted on progress. my family are not aware that I have stopped, I didn't tell them as they would have told me to go back on them as they kept me 'level' headed and I guess is easier for them. I hope you are progressing well. it will take time I guess.

  • Posted

    Are you in the UK? Is it possible to be switched to the capsules with beads there?

    There's a research paper out there that shows the occupancy rate of serotonin receptors at varying dosages of several SSRIs and Venlafaxine. At 37.5 mg the receptors are still bound at 80%, so coming down off that amount is not insignificant! Given that, it is criminal that the drug makers don't provide much smaller dosages to help people come off! I have the beads and am down to the final bead!

    • Posted

      Hi Zen,

      Yes i am in the UK.

      Can you please explain what you mean by the receptors being 80% bound?

      i have read somewhere that if you are reducing with individual beads, not all beads have the active ingredient... so this is a bit hit and miss.

      DAY 3 today of the reduction in tablet form and feel very strange, did not sleep well either.

      x

  • Posted

    Hi

    Yes I'm in the UK. we don't have the beads here, or rather they don't BUY the beads here my GP gave me a liquid form and told me to reduce over a 2 week period (which sounds a bit quick to me) which I am going to start next week hopefully. I can't believe you are taking one bead! I hope it all goes well for you, and yes why don't the companies produce a smaller dose if indeed it is proven to remain at 80% as you say. Good luck with your battle!

  • Posted

    Hopefully you will be one of the lucky ones who can do it in two weeks, but know this: If the wheels come off the bus, it is because your GP made you taper too fast, not because you "need" the meds like a diabetic needs insulin. That concept is a myth with ADs. Be prepared to reinstate at the dose you were at before symptoms got bad, and ask your GP to keep prescribing the liquid so you can come off incrementally.

    Good luck!

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.