Coming off mirtazapine

Posted , 11 users are following.

I thought I would start a new thread to give people tips for coming off this drug. I have gained so much advice and support from people on here and I owe my (so far) painless withdrawal to them. People like Calmer and Betsy, and plenty others too. I have been on 30mg mirtazapine for four years. I tried to come off them a couple of years ago and failed miserably, returning to my full dose after 10 days of awful anxiety and insomnia, as well as migraines and nausea. I had cut my dose to 15mg for a week and then dropped to zero.

This time I read every thread on here about mirtazapine withdrawal and started off really slowly, cutting down by just 3.75mg for two weeks. Then by a further 3.75 mg. At the same time I started taking a lot of inositol. I take a huge heaped teaspoon in my tea every morning. I had only slight nausea when I first started dropping my dose but I think that was me getting used to the inositol. Once I was down to 22.5mg of mirt, with no withdrawal symptoms, I figured I could go a bit faster and dropped my dose down to 15mg. I had no withdrawal symptoms after ten days and so have now dropped my dose to 11.25mg. I use a simple pill cutter from ebay to cut my tablets. So I am now on three quarters of a 15mg tablet. Mirtazapine had pooped out on me and so I already have terrible insomnia. I take temazepam some nights and benadryl on others to help me with that.

I will post my progress here. Who knows, I may fail miserably, but whatever the outcome, I hope it will help others. I was terrified of coming off mirtazapine, but now I am excited by it. I think the key is to take it really slowly and work out the pace your body can cope with. The smaller your dose goes, thee smaller the decrease in your dose should be. Good luck everyone, and please post your own experiences here. I know some people have really suffered despite coming off mirt very slowly. Everyone is different and I think everyone's experience can be a real help to others.

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  • Posted

    This is so very strange. My second day of 3.75mg and I am ravenously hungry. I am snack, snack, snack. I started this guzzling shortly after dropping from 7.5mg to 5.6, and today I just have no will power at all! Just eat eat eat! Quite the opposite to what I expected to happen. Any explanations?
    • Posted

      Man, I am not liking hearing about this!  I have no idea why that would be!!  I'll check with the mirt group!
  • Posted

    Well day 9 started to fall apart for me. Had four mini panic attacks. So I decided to try the venalex again. That stuff has really messed me up. Sickness, headaches, confusion, shakes and if I'd got a gun I would have blown my head off. It's like a hangover from hell. I'm still in bed nearly 34 hours later.
    • Posted

      Sounds awful!  Have you taken the ven, si, and if so how much?  How are you feeling after that? Is that one you'd been on before?
    • Posted

      Si, I am still sure you are in Mirt' withdrawal, it's horrible, hang on in there and take advice.  If it all gets too much for you go to your nearest hospital, I would advice to go back to the 15 mg of Mirt every day until this WD settles, but I'm not sure what else you've taken.

      What is the VENALEX you just say you've taken??  Do you mean Venlafaxine (which is also called Efexor).

      You'll be ok, try and think what you've taken?

    • Posted

      Please be careful about taking more stuff, other than what you've been withdrawing from, without a doctor's approval.. oh, forgot they're pretty incompetent over there!  No, seriously, I got into trouble with taking a new med while in WD from Effexor, and that was WITH a doctor's approval!  I was Rx'd Viibryd which had a paradoxical affect - extreme anxiety, depression and insomnia 100X worse than before!
  • Posted

    Day four on 3.75mg and still no withdrawal symptoms. I'm either very lucky or have tapered down slowly enough not to have them. I'm not complacent though and every day I am expecting things to change. But if it carries on as good as it has so far, then I will be completely off mirtazapine by the end of this month.

    I'm still eating too much, but it's not as bad as it was two days ago thankfully, and is controllable.

    • Posted

      Good, evergreen!  Just did a cut to 14.2 mg a few days ago and no real issues, yet.  I'm going to try to speed this along a little bit.  The only thing I'm noticing after the cut is that I sleep HARD into the morning.  As long as I can keep my sleep, I'll try to get down a little quicker, but that is the one I worry about the most.  

      I'm also on Effexor so hoping that will buffer the taper.  I want to get down to 7.5 mg mirt and then focus on the Effexor taper for awhile.

      I hope you keep traveling well!

       

    • Posted

      If I was still sleeping on mirt I would be tapering MUCH slower than I am, but I have nothing to lose there. I hope it continues well for you.
    • Posted

      8 days at 7.5 mg, the fatigue is more apparent in the afternoon, and the eyes are weary and look watery, so am looking my age !!  Damn !! haha.  Yes 7.5 is definately more sedating than 15 mg, for me.  

      I think I may have a virus, at least it feels like a virus, it's hard to tell, but it sits and is warm on the chest, so I'm putting it down to a virus.

      Evergreen, you're doing so well, you're one of the 1% (maybe) who don't have any WD effects, brilliant for you.

      Yes Betsy, I sleep hard into the morning at the lower dose now, I understand what you mean.  And its worth a mention also, that when I have a late night I can't get to sleep, and then wake earlier and cannot get back to sleep (like last night) - just bear this in mind really, I think rushing may well have a greater effect on your pattern, who knows ... so, early night tonight for me !

      It would be interesting to wear a "Fit band" for a few days and nights, it can assess your sleep, amongst many other things, it tells you if its good quality sleep or not, my daughter has one, maybe she'll let me lend it when she's had her fussy out of it.  

      Enjoy your weeked ladies.

      I hope Si is alright.

       

    • Posted

      Well, I held at 15 for 3 weeks.  This Wednesday, I cut by 8% which was more than I wanted to do but I had forgotten to weigh out my doses for the next two weeks and I didn't feel like fiddling with getting 5%.  Then, the next day I weighed out two weeks and got the 5% so actually went up slightly for the next two nights.  This morning I woke up feeling ok, beautiful day so maybe I'd work on a few projects outside...

      I went out to feed the horses, let the chickens out and feed the sheep.  I raise sheep and it is lambing time.  I found a ewe who had been in labor a long time and the lamb was stuck so I had to pull it.  I had died during labor.  I wasn't devastated like I would be for losing a pet, just thought "crap, these things happen, what a bummer..." But since then, my mood has slipped considerably, I feel negative and cranky, and even weepy.  Negative thoughts creeping in.  I seem to have slipped into a wave, triggered by this loss.  Now I feel like staying on the couch all day :-(

      I'm going to force myself to go on a walk with the dogs and my husband around our property, and hopefully it will pull me back up a bit.  I seem to be incredibly sensitive - grrr!

    • Posted

      So sorry Betsy, that is a very sad loss, in your own hands, what a shock it must be to have seen that happening ~ allow yourself to feel it but don't allow yourself to wallow, just keep 50% above the line, you'll rise soon enough.  Bat those negative thoughts aside, it is possible, practice, even when you're low.  I like the "I'm going to force myself" bit ... that's the spirit.  I hope your walk was helpful, early to expect yourself to be 100%.

      I don't think going to 8% instead of 5% would make you feel like this; it's upsetting to see life disappear.  Be kind to yourself, you did your best and that's all youu or anyone could do.

      Best wishes  x

       

    • Posted

      Losing animals is always extremely sad and puts a real downer on your mood. I feed the wild birds and one day a lesser spotted woodpecker flew against our window and didn't recover. They are so rare and I cried and was depressed about it for days. At the time I was on 30mg of mirt and stable.
    • Posted

      I hope you feel better soon, Calmer. I think that it probably is a virus as you suspect. I think that when we are withdrawing from these meds, it is easy to put everything bad that we feel down to withdrawal, when the truth is we get headaches, nausea, feeling down, fatigue etc in normal life. I have a migraine coming on, but it is something I have suffered with for thirty years. The mirt mosty got rid of them, but I expect they will come back as I return to my natural state, along with my allergies and itching.
    • Posted

      You're so right Evergreen, I won't put this down to wd, it's the familiar kind of symptoms of a virus. I'm practicing positivity as much as I am able!

      Migraines are so painful, I hope it doesn't linger for you.

      I hope you are ok Betsy, sad day for you yesterday, sending kind thoughts your way.

      X

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