Concerned about new research from Imperial College demonstrating micro fractures after biphosphanate

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I am due to have yearly infusion of zoledronic acid when this new research was published. It was only a small study but evidence was overwhelming. It shows although bone gets denser with treatment but becomes brittle prone to fracture. Due to have treatment Wednesday but now don't know what to do. 

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  • Posted

    Hi Jennifer. Agree totally with Anhaga ..... nothing, absolutely nothing, would make me take any kind of  bisophonate. The research I have done over the last 4 months has horrified me.  I cannot believe that the uk gp's are so keen to write a prescription for them, without doing any further tests to investigate what is causing the loss of bone density. (If there is any loss of bone density??   Sometimes the dexa scans are so unreliable.   The Smallest  misplacement of the scan can give such a false reading. The dexa scanners were designed and produced by the very same drug companies that manufacture and sell the bisophonates?  I wish some health journalists would investigate.  This is our lives and our health which is being ruined. I am going with exercise and diet. Good lucj 

    • Posted

      I wouldn't be surprised if sometime in the future this wholescale prescribing of OP meds is going to be looked on as strange as bloodletting!  Not that I really blame the physicians.  They are too busy to keep themselves properly informed and too easily influenced by those with moneymaking in mind.

       

  • Posted

    You could actually be in a position to have a rest from all the drugs. When you find out your tscores and they are better than -2.5 you should not be on the drugs anyway!

    I do not take any of the drugs because of what you have stated and also concerns with swallowing and damage to oesophageas. 

  • Posted

    There is a lovely translated article  available on line from a French Doctor who was at the WHO's 2 day meeting when they were setting the level for when a patient moves out of osteopenia into osteoporosis (and therefore is advised to take medication) .... he says, it was late, it was the end of the conference, it was a hot Friday afternoon ... we had to draw the line somewhere .... someone put a line at -2.5 and that was that, we could go home!

    ?Have you done your risk fracture assessment?  This is available at Sheffield University's website at https://www.shef.ac.uk/FRAX[/b]/

    ?I have a hip score of -2.7 but I will not take any medication.  My risk of a fracture score puts me in the bracket where I do not need to.  It is not just about Tscore but about a whole lot more.

    ?Also,there are pages and pages of info online about the inaccuracies of Dexa scans and in particular how individuals with a small frame (5'2" and under) never started out with a "normal" adults bone mass, so how can they possilbe sustain it.  My wrists are 5.5", my friend's wrists are 7".  How can my bone mass be compared to her.

    • Posted

      Ju st done Sheffield  risk assessment came up as 32 % risk and 12%for hip fracture within 10years . Have been on steroids a lot in past so I think will have to have the treatment 
    • Posted

      I agree about body build.  My writs are also less than 6" and I am quite light.  I believe different criteria are used for determining osteoporosis levels in other countries, depending on ethnicity, so a small-framed Indian woman is not expected to have same bone density as someone from a a country where people are generally larger and heavier-framed.  I think the DXA scan is a useful guide so we know where we are.  i also think the osteoporosis drugs should be reserved for those who are in dire straits, not as a preventative measure for someone who could quite easily use natural means to achieve the same, or better, end.

  • Posted

    My first question is who is Imperial College? The studies on these shots have pretty much been the same as long as I have been researching them.  Still on the fence myself. I was cleared to have Prolia but not sure if I should but I need to according to the Doctors...
    • Posted

      Research was carried out Imperial college London it was only a small study but it used a new form of x ray imaging which hasn't been used before.  It demonstrated the small cracks in bone that hasn't been imaged before. It was reported on BBC 4 2weeks ago.google Imperial college biphosphonate research to see full study.

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