Couple of odd questions for Barretts/anyone...
Posted , 4 users are following.
Hi,
I could put up with my symptoms if I had to - the only thing I'm intrested in is preventing Barrett's or worse. So...
1) I believe that it requires acid AND bile to cause Barrett's and OC? Shouldn't we focus on a diet that would cause little or no bile to be produced, or is that totally impractical?
2) Sucralfate (Carafate) sounds like it would be good for preventing Barrett's and OC. Has this ever been studied?
Thanks
1 like, 5 replies
Barretts herdygerdy
Posted
A diet that is low in fats will reduce the possibility of bile entering the stomach (but some fats are required in a normal diet). So we cannot guarantee to keep all bile out of the stomach.
As you say, it requires reflux into the oesophagus from the stomach of acid and bile to cause the development of Barrett's Oesophagus. There are no effective drugs to reduce bile but there are effective drugs to reduce the acid.
Sucralfate does form a protective extra lining in the stomach to defend the gastric mucosa from acid hyper-secretion. However, it does not remain long enough within the oesophagus as the peristalsis and gravity help the mucous produced there to wash it down into the stomach. Gaviscon acts similarly and, whether it is stickier or a different density, may stay a little longer, whilst also floating on top of the stomach contents like a blanket to help contain reflux.
But to reduce risk of developing Barrett's, at least one of the elements of reflux, acid, bile needs to be kept in check.
herdygerdy Barretts
Posted
mack_1946 herdygerdy
Posted
Barretts herdygerdy
Posted
(Note the careful wording.)
mack_1946 herdygerdy
Posted